Three-dimensional optical tomographic imaging of breast in a human subject

Huabei Jiang; Yong Xu; Nicusor Iftimia; Julie Eggert; Karin Klove; Lisa Baron; Laurie Fajardo

doi:10.1109/42.974928

Three-dimensional optical tomographic imaging of breast in a human subject

Huabei Jiang, Yong Xu, Nicusor Iftimia, Julie Eggert, Karin Klove, Lisa Baron, Laurie Fajardo

Research output: Contribution to journal › Article › peer-review

104 Scopus citations

Abstract

We present for the first time of a full three-dimensional (3-D) reconstruction of absorption images of breast from continuous-wave (cw) measurements performed on a premenopausal woman. Our 3-D optical images clearly reveal a large primary tumor as well as a small secondary tumor in a separate location of the breast. The multiple tumors identified by our 3-D optical imaging have been confirmed by the subsequent biopsy examination of the breast. Quantitative information of the optical images obtained is provided in terms of the location, size, and absorption coefficient of the tumors.

Original language	English (US)
Pages (from-to)	1334-1340
Number of pages	7
Journal	IEEE Transactions on Medical Imaging
Volume	20
Issue number	12
DOIs	https://doi.org/10.1109/42.974928
State	Published - Dec 2001
Externally published	Yes

Keywords

Breast diffuse optical tomography
Photon migration
Three-dimensional image reconstruction

ASJC Scopus subject areas

Software
Radiological and Ultrasound Technology
Computer Science Applications
Electrical and Electronic Engineering

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10.1109/42.974928

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title = "Three-dimensional optical tomographic imaging of breast in a human subject",

abstract = "We present for the first time of a full three-dimensional (3-D) reconstruction of absorption images of breast from continuous-wave (cw) measurements performed on a premenopausal woman. Our 3-D optical images clearly reveal a large primary tumor as well as a small secondary tumor in a separate location of the breast. The multiple tumors identified by our 3-D optical imaging have been confirmed by the subsequent biopsy examination of the breast. Quantitative information of the optical images obtained is provided in terms of the location, size, and absorption coefficient of the tumors.",

keywords = "Breast diffuse optical tomography, Photon migration, Three-dimensional image reconstruction",

author = "Huabei Jiang and Yong Xu and Nicusor Iftimia and Julie Eggert and Karin Klove and Lisa Baron and Laurie Fajardo",

note = "Funding Information: Manuscript received November 30, 2000; revised September 26, 2001. This work was supported in part the National Institutes of Health (NIH) under Grant CA 78 334 and in part by the Greenville Hospital System/Clemson University Biomedical Cooperative. The Associate Editor responsible for coordinating the review of this paper and recommending its publication was M. W. Vannier. Asterisk indicates corresponding author. *H. Jiang is with the Biomedical Optics Laboratory, Department of Physics & Astronomy, Clemson University, Clemson, SC 29634-0978 USA (e-mail: hjiang@clemson.edu).",

year = "2001",

month = dec,

doi = "10.1109/42.974928",

language = "English (US)",

volume = "20",

pages = "1334--1340",

journal = "IEEE Transactions on Medical Imaging",

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T1 - Three-dimensional optical tomographic imaging of breast in a human subject

AU - Jiang, Huabei

AU - Xu, Yong

AU - Iftimia, Nicusor

AU - Eggert, Julie

AU - Klove, Karin

AU - Baron, Lisa

AU - Fajardo, Laurie

N1 - Funding Information: Manuscript received November 30, 2000; revised September 26, 2001. This work was supported in part the National Institutes of Health (NIH) under Grant CA 78 334 and in part by the Greenville Hospital System/Clemson University Biomedical Cooperative. The Associate Editor responsible for coordinating the review of this paper and recommending its publication was M. W. Vannier. Asterisk indicates corresponding author. *H. Jiang is with the Biomedical Optics Laboratory, Department of Physics & Astronomy, Clemson University, Clemson, SC 29634-0978 USA (e-mail: hjiang@clemson.edu).

PY - 2001/12

Y1 - 2001/12

N2 - We present for the first time of a full three-dimensional (3-D) reconstruction of absorption images of breast from continuous-wave (cw) measurements performed on a premenopausal woman. Our 3-D optical images clearly reveal a large primary tumor as well as a small secondary tumor in a separate location of the breast. The multiple tumors identified by our 3-D optical imaging have been confirmed by the subsequent biopsy examination of the breast. Quantitative information of the optical images obtained is provided in terms of the location, size, and absorption coefficient of the tumors.

AB - We present for the first time of a full three-dimensional (3-D) reconstruction of absorption images of breast from continuous-wave (cw) measurements performed on a premenopausal woman. Our 3-D optical images clearly reveal a large primary tumor as well as a small secondary tumor in a separate location of the breast. The multiple tumors identified by our 3-D optical imaging have been confirmed by the subsequent biopsy examination of the breast. Quantitative information of the optical images obtained is provided in terms of the location, size, and absorption coefficient of the tumors.

KW - Breast diffuse optical tomography

KW - Photon migration

KW - Three-dimensional image reconstruction

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JO - IEEE Transactions on Medical Imaging

JF - IEEE Transactions on Medical Imaging

IS - 12

ER -

Three-dimensional optical tomographic imaging of breast in a human subject

Abstract

Keywords

ASJC Scopus subject areas

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