Abstract
Although an increased risk of hematologic malignancies in children with Neurofibromatosis-1 (NF-1) is well established, whether adults with NF-1 have an increased risk of such malignancies is unclear. We currently describe two adult patients with NF-1 who rapidly developed secondary myelodysplastic syndromes with abnormalities of chromosome 7 following chemotherapy for AML. We propose that adults with NF-1 also have abnormalities of hematologic progenitor cells.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 605-608 |
| Number of pages | 4 |
| Journal | Leukemia and Lymphoma |
| Volume | 32 |
| Issue number | 5-6 |
| DOIs | |
| State | Published - 1999 |
| Externally published | Yes |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
Keywords
- Acute myelogenous leukemia
- Adult
- Myelodysplastic syndrome
- Neurofibromatosis
ASJC Scopus subject areas
- Hematology
- Oncology
- Cancer Research
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