The Use of Dermabond® as an Adjunct to Wound Closure After Total Knee Arthroplasty: Examining Immediate Post-Operative Wound Drainage

Yaser El-Gazzar; Daniel C. Smith; Sun Jin Kim; David M. Hirsh; Yossef Blum; Marcie Cobelli; Hillel W. Cohen

doi:10.1016/j.arth.2012.07.038

The Use of Dermabond® as an Adjunct to Wound Closure After Total Knee Arthroplasty: Examining Immediate Post-Operative Wound Drainage

Yaser El-Gazzar, Daniel C. Smith, Sun Jin Kim, David M. Hirsh, Yossef Blum, Marcie Cobelli, Hillel W. Cohen

Orthopaedic Surgery

Research output: Contribution to journal › Article › peer-review

36 Scopus citations

Abstract

Wound drainage after total knee arthroplasty (TKA) can be detrimental to surgical outcome. This IRB-approved randomized, prospective, blinded study examined the use of Dermabond® as an adjunct to wound closure after TKA. We proposed that Dermabond® supplementation to wound closure would result in a significant decrease in wound drainage after TKA. After standardized closure, patients were randomized into experimental or control groups with the experimental group receiving Dermabond® supplementation. Standardized dressings were evaluated postoperatively and drainage units were compared using a Mann-Whitney U Test. The median drainage for the Dermabond group (153) was lower than the drainage for the control group (657) at a statistically significant level (P<0.001).

Original language	English (US)
Pages (from-to)	553-556
Number of pages	4
Journal	Journal of Arthroplasty
Volume	28
Issue number	4
DOIs	https://doi.org/10.1016/j.arth.2012.07.038
State	Published - Apr 2013

Keywords

Dermabond
Total knee arthroplasty

ASJC Scopus subject areas

Orthopedics and Sports Medicine

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10.1016/j.arth.2012.07.038

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title = "The Use of Dermabond{\textregistered} as an Adjunct to Wound Closure After Total Knee Arthroplasty: Examining Immediate Post-Operative Wound Drainage",

abstract = "Wound drainage after total knee arthroplasty (TKA) can be detrimental to surgical outcome. This IRB-approved randomized, prospective, blinded study examined the use of Dermabond{\textregistered} as an adjunct to wound closure after TKA. We proposed that Dermabond{\textregistered} supplementation to wound closure would result in a significant decrease in wound drainage after TKA. After standardized closure, patients were randomized into experimental or control groups with the experimental group receiving Dermabond{\textregistered} supplementation. Standardized dressings were evaluated postoperatively and drainage units were compared using a Mann-Whitney U Test. The median drainage for the Dermabond group (153) was lower than the drainage for the control group (657) at a statistically significant level (P<0.001).",

keywords = "Dermabond, Total knee arthroplasty",

author = "Yaser El-Gazzar and Smith, {Daniel C.} and Kim, {Sun Jin} and Hirsh, {David M.} and Yossef Blum and Marcie Cobelli and Cohen, {Hillel W.}",

note = "Funding Information: This publication was supported in part by the CTSA Grant UL1 RR025750, KL2 RR025749 and TL1 RR025748 from the National Center for Research Resources (NCRR), a component of the National Institutes of Health (NIH), and NIH roadmap for Medical Research. Its contents are solely the responsibility of the authors and do not necessarily represent the official view of the NCRR or NIH.",

year = "2013",

month = apr,

doi = "10.1016/j.arth.2012.07.038",

language = "English (US)",

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AU - El-Gazzar, Yaser

AU - Smith, Daniel C.

AU - Kim, Sun Jin

AU - Hirsh, David M.

AU - Blum, Yossef

AU - Cobelli, Marcie

AU - Cohen, Hillel W.

N1 - Funding Information: This publication was supported in part by the CTSA Grant UL1 RR025750, KL2 RR025749 and TL1 RR025748 from the National Center for Research Resources (NCRR), a component of the National Institutes of Health (NIH), and NIH roadmap for Medical Research. Its contents are solely the responsibility of the authors and do not necessarily represent the official view of the NCRR or NIH.

PY - 2013/4

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N2 - Wound drainage after total knee arthroplasty (TKA) can be detrimental to surgical outcome. This IRB-approved randomized, prospective, blinded study examined the use of Dermabond® as an adjunct to wound closure after TKA. We proposed that Dermabond® supplementation to wound closure would result in a significant decrease in wound drainage after TKA. After standardized closure, patients were randomized into experimental or control groups with the experimental group receiving Dermabond® supplementation. Standardized dressings were evaluated postoperatively and drainage units were compared using a Mann-Whitney U Test. The median drainage for the Dermabond group (153) was lower than the drainage for the control group (657) at a statistically significant level (P<0.001).

AB - Wound drainage after total knee arthroplasty (TKA) can be detrimental to surgical outcome. This IRB-approved randomized, prospective, blinded study examined the use of Dermabond® as an adjunct to wound closure after TKA. We proposed that Dermabond® supplementation to wound closure would result in a significant decrease in wound drainage after TKA. After standardized closure, patients were randomized into experimental or control groups with the experimental group receiving Dermabond® supplementation. Standardized dressings were evaluated postoperatively and drainage units were compared using a Mann-Whitney U Test. The median drainage for the Dermabond group (153) was lower than the drainage for the control group (657) at a statistically significant level (P<0.001).

KW - Dermabond

KW - Total knee arthroplasty

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The Use of Dermabond® as an Adjunct to Wound Closure After Total Knee Arthroplasty: Examining Immediate Post-Operative Wound Drainage

Abstract

Keywords

ASJC Scopus subject areas

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