The limited capacity of mammalian cells to accumulate free intracellular methotrexate, a critical intracellular component required for inhibition of dihydrofolate reduction to tetrahydrofolate. A basis, in part, for the efficacy of high dose protocols

J. C. White, I. D. Goldman, W. Lawrence

Research output: Contribution to journalArticlepeer-review

Original languageEnglish (US)
Pages (from-to)No.475
JournalProceedings of the American Association for Cancer Research
StatePublished - Jan 1 1976
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)

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