The impact of preoperative motor weakness on postoperative opioid use after ACDF

Hannah A. Levy; Brian A. Karamian; Jeffrey Henstenburg; Joseph Larwa; Jose A. Canseco; Brett Haislup; Michael Chang; Parthik Patel; Kris E. Radcliff; Barrett I. Woods; Mark F. Kurd; Alan S. Hilibrand; Christopher K. Kepler; Alexander R. Vaccaro; Gregory D. Schroeder

doi:10.1016/j.jor.2021.06.003

The impact of preoperative motor weakness on postoperative opioid use after ACDF

Hannah A. Levy
, Brian A. Karamian
, Jeffrey Henstenburg
, Joseph Larwa
, Jose A. Canseco
, Brett Haislup
, Michael Chang
, Parthik Patel
, Kris E. Radcliff
, Barrett I. Woods
, Mark F. Kurd
, Alan S. Hilibrand
, Christopher K. Kepler
, Alexander R. Vaccaro
, Gregory D. Schroeder

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

This study aims to determine if preoperative weakness is an isolated risk factor for prolonged postoperative opioid use after anterior cervical discectomy and fusion (ACDF). Patients with preoperative weakness were significantly more likely to have prolonged and inappropriate opioid use and have a single prescription mean morphine equivalent (MME) ≥ 200. Logistic regression isolated preoperative weakness, opioid tolerance, depression, and VAS Neck pain as independent predictors of extended opioid use. High postoperative opioid dose (MME ≥ 90) correlated with opioid tolerance, younger age, male sex, greater CCI, prior cervical surgery, and preoperative VAS Neck pain on regression.

Original language	English (US)
Pages (from-to)	23-28
Number of pages	6
Journal	Journal of Orthopaedics
Volume	26
DOIs	https://doi.org/10.1016/j.jor.2021.06.003
State	Published - Jul 1 2021
Externally published	Yes

Keywords

ACDF
Motor weakness
Narcotics
Opioid
Risk factors
Spine surgery

ASJC Scopus subject areas

Orthopedics and Sports Medicine

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10.1016/j.jor.2021.06.003

Cite this

Levy, H. A., Karamian, B. A., Henstenburg, J., Larwa, J., Canseco, J. A., Haislup, B., Chang, M., Patel, P., Radcliff, K. E., Woods, B. I., Kurd, M. F., Hilibrand, A. S., Kepler, C. K., Vaccaro, A. R., & Schroeder, G. D. (2021). The impact of preoperative motor weakness on postoperative opioid use after ACDF. Journal of Orthopaedics, 26, 23-28. https://doi.org/10.1016/j.jor.2021.06.003

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title = "The impact of preoperative motor weakness on postoperative opioid use after ACDF",

abstract = "This study aims to determine if preoperative weakness is an isolated risk factor for prolonged postoperative opioid use after anterior cervical discectomy and fusion (ACDF). Patients with preoperative weakness were significantly more likely to have prolonged and inappropriate opioid use and have a single prescription mean morphine equivalent (MME) ≥ 200. Logistic regression isolated preoperative weakness, opioid tolerance, depression, and VAS Neck pain as independent predictors of extended opioid use. High postoperative opioid dose (MME ≥ 90) correlated with opioid tolerance, younger age, male sex, greater CCI, prior cervical surgery, and preoperative VAS Neck pain on regression.",

keywords = "ACDF, Motor weakness, Narcotics, Opioid, Risk factors, Spine surgery",

author = "Levy, \{Hannah A.\} and Karamian, \{Brian A.\} and Jeffrey Henstenburg and Joseph Larwa and Canseco, \{Jose A.\} and Brett Haislup and Michael Chang and Parthik Patel and Radcliff, \{Kris E.\} and Woods, \{Barrett I.\} and Kurd, \{Mark F.\} and Hilibrand, \{Alan S.\} and Kepler, \{Christopher K.\} and Vaccaro, \{Alexander R.\} and Schroeder, \{Gregory D.\}",

note = "Publisher Copyright: {\textcopyright} 2021 Professor P K Surendran Memorial Education Foundation",

year = "2021",

month = jul,

day = "1",

doi = "10.1016/j.jor.2021.06.003",

language = "English (US)",

volume = "26",

pages = "23--28",

journal = "Journal of Orthopaedics",

issn = "0972-978X",

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T1 - The impact of preoperative motor weakness on postoperative opioid use after ACDF

AU - Levy, Hannah A.

AU - Karamian, Brian A.

AU - Henstenburg, Jeffrey

AU - Larwa, Joseph

AU - Canseco, Jose A.

AU - Haislup, Brett

AU - Chang, Michael

AU - Patel, Parthik

AU - Radcliff, Kris E.

AU - Woods, Barrett I.

AU - Kurd, Mark F.

AU - Hilibrand, Alan S.

AU - Kepler, Christopher K.

AU - Vaccaro, Alexander R.

AU - Schroeder, Gregory D.

PY - 2021/7/1

Y1 - 2021/7/1

N2 - This study aims to determine if preoperative weakness is an isolated risk factor for prolonged postoperative opioid use after anterior cervical discectomy and fusion (ACDF). Patients with preoperative weakness were significantly more likely to have prolonged and inappropriate opioid use and have a single prescription mean morphine equivalent (MME) ≥ 200. Logistic regression isolated preoperative weakness, opioid tolerance, depression, and VAS Neck pain as independent predictors of extended opioid use. High postoperative opioid dose (MME ≥ 90) correlated with opioid tolerance, younger age, male sex, greater CCI, prior cervical surgery, and preoperative VAS Neck pain on regression.

AB - This study aims to determine if preoperative weakness is an isolated risk factor for prolonged postoperative opioid use after anterior cervical discectomy and fusion (ACDF). Patients with preoperative weakness were significantly more likely to have prolonged and inappropriate opioid use and have a single prescription mean morphine equivalent (MME) ≥ 200. Logistic regression isolated preoperative weakness, opioid tolerance, depression, and VAS Neck pain as independent predictors of extended opioid use. High postoperative opioid dose (MME ≥ 90) correlated with opioid tolerance, younger age, male sex, greater CCI, prior cervical surgery, and preoperative VAS Neck pain on regression.

KW - ACDF

KW - Motor weakness

KW - Narcotics

KW - Opioid

KW - Risk factors

KW - Spine surgery

UR - https://www.scopus.com/pages/publications/85109152619

UR - https://www.scopus.com/pages/publications/85109152619#tab=citedBy

U2 - 10.1016/j.jor.2021.06.003

DO - 10.1016/j.jor.2021.06.003

M3 - Article

AN - SCOPUS:85109152619

SN - 0972-978X

VL - 26

SP - 23

EP - 28

JO - Journal of Orthopaedics

JF - Journal of Orthopaedics

ER -

The impact of preoperative motor weakness on postoperative opioid use after ACDF

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

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