TY - JOUR
T1 - The Canadian Study of Diet, Lifestyle, and Health
T2 - Design and characteristics of a new cohort study of cancer risk
AU - Rohan, Thomas E.
AU - Soskolne, Colin L.
AU - Carroll, Kenneth K.
AU - Kreiger, Nancy
N1 - Funding Information:
Establishment of the cohort was supported by grants from the National Cancer Institute of Canada and from the Canadian Institutes of Health Research. The Canadian Cancer Society, the Department of Alumni and Development at the University of Toronto (Rivi Frankle and Barbara Dick), the Department of Alumni Relations and Development at the University of Western Ontario (Jim Ferguson and Sara Steers), and The Office of Alumni Affairs at the University of Alberta (Susan Peirce and Rick Pilger), and all of the participants who continue to provide valuable information to this study are acknowledged with thanks. We thank Richard Gallagher for his contributions to the study, and we thank Vicki Kirsh and Scott Leatherdale for their contributions to the further development of the cohort.
PY - 2007
Y1 - 2007
N2 - Background: We have established a new cohort study, the Canadian Study of Diet, Lifestyle, and Health, to investigate the relationship between diet, lifestyle factors, molecular markers, and cancer incidence in Canada. Methods: The cohort was established predominantly by recruiting alumni from the Universities of Alberta, Toronto, and Western Ontario between 1995 and 1998, but also includes a small contingent recruited mostly in 1992 through the Canadian Cancer Society. Participants completed baseline lifestyle and food frequency questionnaires, measured waist and hip circumferences, and provided hair and toenail specimens. Results: Seventy-three thousand nine hundred and nine individuals (34,291 males and 39,618 females) were recruited, with representation from all Canadian provinces and territories; 97% provided biological specimens. The mean (S.D.) ages of the male and female participants at recruitment were 51.6 (15.6) and 46.1 (15.2) years, respectively. Data from a random sample of the study subjects at baseline show that approximately one-half of the males and one-third of the females were overweight (BMI ≥ 25 kg/m2), and approximately one-quarter of all participants reported that they walked at least 4 h/week. Mean (S.D.) daily caloric intake was 2341 (697) kcal for males and 2091 (612) kcal for females. Conclusions: Given the rich repository of questionnaire and biological data, and an average follow-up time for cohort members of 10.4 years, the study is poised to make a major Canadian contribution towards understanding the roles of diet, lifestyle factors, and molecular markers in influencing cancer risk.
AB - Background: We have established a new cohort study, the Canadian Study of Diet, Lifestyle, and Health, to investigate the relationship between diet, lifestyle factors, molecular markers, and cancer incidence in Canada. Methods: The cohort was established predominantly by recruiting alumni from the Universities of Alberta, Toronto, and Western Ontario between 1995 and 1998, but also includes a small contingent recruited mostly in 1992 through the Canadian Cancer Society. Participants completed baseline lifestyle and food frequency questionnaires, measured waist and hip circumferences, and provided hair and toenail specimens. Results: Seventy-three thousand nine hundred and nine individuals (34,291 males and 39,618 females) were recruited, with representation from all Canadian provinces and territories; 97% provided biological specimens. The mean (S.D.) ages of the male and female participants at recruitment were 51.6 (15.6) and 46.1 (15.2) years, respectively. Data from a random sample of the study subjects at baseline show that approximately one-half of the males and one-third of the females were overweight (BMI ≥ 25 kg/m2), and approximately one-quarter of all participants reported that they walked at least 4 h/week. Mean (S.D.) daily caloric intake was 2341 (697) kcal for males and 2091 (612) kcal for females. Conclusions: Given the rich repository of questionnaire and biological data, and an average follow-up time for cohort members of 10.4 years, the study is poised to make a major Canadian contribution towards understanding the roles of diet, lifestyle factors, and molecular markers in influencing cancer risk.
KW - Cancer
KW - Cohort studies
KW - Diet
KW - Epidemiology
KW - Lifestyle
KW - Molecular markers
KW - Personal medical history
KW - Questionnaire
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UR - http://www.scopus.com/inward/citedby.url?scp=33847632604&partnerID=8YFLogxK
U2 - 10.1016/j.cdp.2006.12.006
DO - 10.1016/j.cdp.2006.12.006
M3 - Article
C2 - 17303348
AN - SCOPUS:33847632604
SN - 0361-090X
VL - 31
SP - 12
EP - 17
JO - Cancer detection and prevention
JF - Cancer detection and prevention
IS - 1
ER -
