TY - JOUR
T1 - The association between body mass index and outcome after coronary artery bypass grafting operations
AU - Devarajan, Jagan
AU - Vydyanathan, Amaresh
AU - You, Jing
AU - Xu, Meng
AU - Sessler, Daniel I.
AU - Sabik, Joseph F.
AU - Bashour, Allen
N1 - Publisher Copyright:
© The Author 2016. Published by Oxford University Press on behalf of the European Association for Cardio-Thoracic Surgery. All rights reserved.
PY - 2016/8/1
Y1 - 2016/8/1
N2 - OBJECTIVES: This investigation was undertaken to analyse the association between body mass index (BMI) and morbidity after coronary artery bypass graft (CABG) operations. METHODS: The setting was a cardiovascular intensive care unit (ICU) of a tertiary medical referral centre. This was a retrospective review; patients were classified according to their BMI into five groups: underweight <18.5 kg/m2; normal weight 18.5-24.9 kg/m2; overweight 25-29.9 kg/m2; Class I obesity 3034.9 kg/m2; and Class II/III obesity >35 kg/m2. We included patients who underwent isolated CABG between January 3, 2006 and March 8, 2011. After including only the initial operation or admission in patients with more than one operation or hospital admission and excluding patients with any missing variable, 3470 patients remained in the analyses. The primary outcomes analysed were hospital mortality and pulmonary and infection morbidities. We secondarily assessed the association between BMI category and each of the three outcomes. RESULTS: Respective mortality, and pulmonary and infection morbidity occurrence rates were: 8.7, 13.0 and 13.0% for the underweight; 2.4, 8.0 and 4.8% for the overweight; 1.8, 10.9 and 5.6% for the Class I obesity group; and 2.7, 11.1 and 5.7% for the Class II/III obesity group, vs 2.3, 7.0 and 6.2% for the normal weight group. Class I and II/III obesity patients were more likely to have pulmonary morbidity compared with the normal weight group, after adjusting for the potential confounding variables. CONCLUSIONS: Class I and Class II/III obesity (BMI ≥ 30 kg/m2) was associated with increased pulmonary morbidity after CABG operations. There was no difference in mortality or infection morbidity in any BMI group compared with the normal group.
AB - OBJECTIVES: This investigation was undertaken to analyse the association between body mass index (BMI) and morbidity after coronary artery bypass graft (CABG) operations. METHODS: The setting was a cardiovascular intensive care unit (ICU) of a tertiary medical referral centre. This was a retrospective review; patients were classified according to their BMI into five groups: underweight <18.5 kg/m2; normal weight 18.5-24.9 kg/m2; overweight 25-29.9 kg/m2; Class I obesity 3034.9 kg/m2; and Class II/III obesity >35 kg/m2. We included patients who underwent isolated CABG between January 3, 2006 and March 8, 2011. After including only the initial operation or admission in patients with more than one operation or hospital admission and excluding patients with any missing variable, 3470 patients remained in the analyses. The primary outcomes analysed were hospital mortality and pulmonary and infection morbidities. We secondarily assessed the association between BMI category and each of the three outcomes. RESULTS: Respective mortality, and pulmonary and infection morbidity occurrence rates were: 8.7, 13.0 and 13.0% for the underweight; 2.4, 8.0 and 4.8% for the overweight; 1.8, 10.9 and 5.6% for the Class I obesity group; and 2.7, 11.1 and 5.7% for the Class II/III obesity group, vs 2.3, 7.0 and 6.2% for the normal weight group. Class I and II/III obesity patients were more likely to have pulmonary morbidity compared with the normal weight group, after adjusting for the potential confounding variables. CONCLUSIONS: Class I and Class II/III obesity (BMI ≥ 30 kg/m2) was associated with increased pulmonary morbidity after CABG operations. There was no difference in mortality or infection morbidity in any BMI group compared with the normal group.
KW - Anesthesia
KW - BMI
KW - CABG surgery
KW - Critical care
KW - Morbidity
KW - Outcome
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U2 - 10.1093/ejcts/ezv483
DO - 10.1093/ejcts/ezv483
M3 - Article
C2 - 26825108
AN - SCOPUS:84992497979
SN - 1010-7940
VL - 50
SP - 344
EP - 349
JO - European Journal of Cardio-thoracic Surgery
JF - European Journal of Cardio-thoracic Surgery
IS - 2
M1 - ezv483
ER -