Abstract
The adrenal glands from 9 patients with hereditary adreno leukodystrophy were studied. Unique changes were found in the zona fasciculata and reticularis in 8 of the cases. These changes consisted of ballooned cortical cells, many of which had a striated cytoplasm with macrovacuoles. This spectrum of change suggests that the evolution of adrenal atrophy in this disease is a primary adrenolytic process. An autoimmune process, previously proposed in this condition, now seems unlikely.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 305-310 |
| Number of pages | 6 |
| Journal | Archives of Pathology and Laboratory Medicine |
| Volume | 96 |
| Issue number | 5 |
| State | Published - Dec 1 1973 |
ASJC Scopus subject areas
- Pathology and Forensic Medicine
- Medical Laboratory Technology