@article{0bc8230b2eb64a8bbf24f0701b1a0471,
title = "The 5-Cog paradigm to improve detection of cognitive impairment and dementia: clinical trial protocol",
abstract = "Cognitive impairment related to dementia is under-diagnosed in primary care despite availability of numerous cognitive assessment tools; under-diagnosis is more prevalent for members of racial and ethnic minority groups. Clinical decision-support systems may improve rates of primary care providers responding to positive cognitive assessments with appropriate follow-up. The 5-Cog study is a randomized controlled trial in 1200 predominantly Black and Hispanic older adults from an urban underserved community who are presenting to primary care with cognitive concerns. The study will validate a novel 5-minute cognitive assessment coupled with an electronic medical record-embedded decision tree to overcome the barriers of current cognitive assessment paradigms in primary care and facilitate improved dementia care.",
keywords = "clinical trial protocol, cognitive assessment, cognitive impairment, cognitive screening, dementia, dissemination and implementation science, randomized controlled trial",
author = "Rachel Chalmer and Emmeline Ayers and Weiss, {Erica F.} and Rubina Malik and Amy Ehrlich and Cuiling Wang and Jessica Zwerling and Asif Ansari and Possin, {Katherine L.} and Joe Verghese",
note = "Funding Information: This work is supported by a grant from National Institute of Neurological Disorders and Stroke of the National Institutes of Health under Award Numbers UG3NS105565 and UH3NS105565. The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed. No writing assistance was utilized in the production of this manuscript. Funding Information: The 5-Cog Paradigm to Improve Detection of Cognitive Impairment and Dementia is a single-blind, randomized controlled trial (RCT) validating the ability of the paradigm to achieve {\textquoteleft}improved dementia care{\textquoteright} among 1200 OAs with cognitive concerns presenting to primary care in an urban, underserved community-based practice within a large academic health system. The paradigm consists of the 5-Cog – a novel, nonliteracy-biased, and easy to use brief cognitive assessment (BCA) – paired with a Clinical Decision-Support System (CDSS) in the form of an electronic medical record (EMR)-embedded decision tree. The 5-Cog study is a participant in the Consortium for the Detection of Cognitive Impairment, Including Dementia (DetectCID) funded by the National Institute of Neurological Disorders and Stroke of the NIH, collaborating around the development, implementation and dissemination of improved paradigms for detection and management of dementia. The 5-Cog study is registered on clinicaltrials.gov (NCT03816644). Publisher Copyright: {\textcopyright} 2022 Future Medicine Ltd.",
year = "2022",
month = aug,
doi = "10.2217/nmt-2021-0043",
language = "English (US)",
volume = "12",
pages = "171--184",
journal = "Neurodegenerative disease management",
issn = "1758-2024",
publisher = "Future Medicine Ltd.",
number = "4",
}