TandemHeart device as rescue therapy in the management of acute heart failure

Siyamek Neragi-Miandoab, Daniel Goldstein, David A. D'Alessandro

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


Background: The TandemHeart device (THD) is a pump system that can be deployed percutaneously (PC) or via conventional surgical (CS) cannulation; it is capable of supporting one or both ventricles. It is a versatile system designed for use as a rescue device in acute heart failure and as a bridge to decision in moribund patients. Methods: Retrospective analysis was conducted on all patients who underwent a THD implant; either PC or CS; at our institution. Univariate analysis was done using Fisher's exact and Chi-square tests for categorical variables and Wilcoxon Rank Sum test for continuous ones. Results: 51 adult patients were identified: 10 PC and 41 CS. Mean age was 58.9 ± 12.8 years, and 31% were female. In hospital mortality was 61%. Univariate predictors of death were prolonged support (74% versus 46%, P = .04) and higher lactic acid levels (5.3 ± 4.9 versus 2.3 ± 1.9 mmol/L, P = .012). The length of stay (LOS) for survivors was 59.8 ± 30.0 days. Conclusion: Uni- or bi-ventricular unloading can be successfully achieved using the THD, either trans-thoracically or percutaneously, with an acceptable complication profile.

Original languageEnglish (US)
Pages (from-to)E160-E162
JournalHeart Surgery Forum
Issue number3
StatePublished - Jun 2014

ASJC Scopus subject areas

  • Surgery
  • Cardiology and Cardiovascular Medicine


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