Structure and function of mammalian cilia

Peter Satir, Søren T. Christensen

Research output: Contribution to journalReview articlepeer-review

153 Scopus citations


In the past half century, beginning with electron microscopic studies of 9 + 2 motile and 9 + 0 primary cilia, novel insights have been obtained regarding the structure and function of mammalian cilia. All cilia can now be viewed as sensory cellular antennae that coordinate a large number of cellular signaling pathways, sometimes coupling the signaling to ciliary motility or alternatively to cell division and differentiation. This view has had unanticipated consequences for our understanding of developmental processes and human disease.

Original languageEnglish (US)
Pages (from-to)687-693
Number of pages7
JournalHistochemistry and Cell Biology
Issue number6
StatePublished - Jun 2008
Externally publishedYes


  • Ciliopathies
  • Motile cilia
  • Motility
  • Primary cilia
  • Sensory organelles
  • Signaling

ASJC Scopus subject areas

  • Histology
  • Molecular Biology
  • Medical Laboratory Technology
  • Cell Biology


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