Streptococcal toxic shock syndrome due to noninvasive pharyngitis

Edward K. Chapnick, Jeremy D. Gradon, Larry I. Lutwick, John Kim, Michael Levi, Michael H. Kim, Patrick M. Schlievert

Research output: Contribution to journalArticlepeer-review

52 Scopus citations


Serious infections due to group A β-hemolytic streptococcus (GABHS) have been reported with increasing frequency in recent years. We report a case of toxic shock syndrome (TSS) due to GABHS pharyngitis in an otherwise healthy 14-year-old boy. The organism was found to produce toxin A. To our knowledge, this is the second reported case of streptococcal TSS associated with the production of toxin A that is not associated with an invasive disease and the first case associated with a documented rise in the level of antibody to the streptococcal toxin itself. Clinicians must be especially vigilant for this entity in patients who have streptococcal pharyngitis because early recognition and institution of aggressive supportive therapy can be lifesaving.

Original languageEnglish (US)
Pages (from-to)1074-1077
Number of pages4
JournalClinical Infectious Diseases
Issue number5
StatePublished - May 1 1992

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases


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