Steroid-responsive inclusion body myositis associated with endometrial cancer

Doru T. Alexandrescu; Niyati S. Bhagwati; Barry Fomberstein; David E. Wolfe; Aaron Feliz; Peter H. Wiernik

Steroid-responsive inclusion body myositis associated with endometrial cancer

Doru T. Alexandrescu, Niyati S. Bhagwati, Barry Fomberstein, David E. Wolfe, Aaron Feliz, Peter H. Wiernik

Research output: Contribution to journal › Article › peer-review

Abstract

Inclusion body myositis (IBM) is an uncommon chronic inflammatory myopathy. Although the association between other myopathies and cancer has been well established, the relationship between IBM and neoplasia is not completely understood. Unlike polymyositis (PM) or dermatomyositis (DM), IBM rarely responds to immunosuppressive treatment and the response is seldom long-lasting. We describe a case of IBM associated with endometrial carcinoma that also demonstrated a unique response to steroids alone which persisted despite cancer relapse. The factors that are associated with a response of IBM to steroids are discussed. An atypical, steroid-responsive form of the disease is delineated.

Original language	English (US)
Pages (from-to)	93-96
Number of pages	4
Journal	Clinical and Experimental Rheumatology
Volume	23
Issue number	1
State	Published - Jan 2005
Externally published	Yes

Keywords

Atypical
Endometrial carcinoma
Inclusion body myositis
Steroids

ASJC Scopus subject areas

Rheumatology
Immunology and Allergy
Immunology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Cite this

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title = "Steroid-responsive inclusion body myositis associated with endometrial cancer",

abstract = "Inclusion body myositis (IBM) is an uncommon chronic inflammatory myopathy. Although the association between other myopathies and cancer has been well established, the relationship between IBM and neoplasia is not completely understood. Unlike polymyositis (PM) or dermatomyositis (DM), IBM rarely responds to immunosuppressive treatment and the response is seldom long-lasting. We describe a case of IBM associated with endometrial carcinoma that also demonstrated a unique response to steroids alone which persisted despite cancer relapse. The factors that are associated with a response of IBM to steroids are discussed. An atypical, steroid-responsive form of the disease is delineated.",

keywords = "Atypical, Endometrial carcinoma, Inclusion body myositis, Steroids",

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TY - JOUR

T1 - Steroid-responsive inclusion body myositis associated with endometrial cancer

AU - Alexandrescu, Doru T.

AU - Bhagwati, Niyati S.

AU - Fomberstein, Barry

AU - Wolfe, David E.

AU - Feliz, Aaron

AU - Wiernik, Peter H.

PY - 2005/1

Y1 - 2005/1

N2 - Inclusion body myositis (IBM) is an uncommon chronic inflammatory myopathy. Although the association between other myopathies and cancer has been well established, the relationship between IBM and neoplasia is not completely understood. Unlike polymyositis (PM) or dermatomyositis (DM), IBM rarely responds to immunosuppressive treatment and the response is seldom long-lasting. We describe a case of IBM associated with endometrial carcinoma that also demonstrated a unique response to steroids alone which persisted despite cancer relapse. The factors that are associated with a response of IBM to steroids are discussed. An atypical, steroid-responsive form of the disease is delineated.

AB - Inclusion body myositis (IBM) is an uncommon chronic inflammatory myopathy. Although the association between other myopathies and cancer has been well established, the relationship between IBM and neoplasia is not completely understood. Unlike polymyositis (PM) or dermatomyositis (DM), IBM rarely responds to immunosuppressive treatment and the response is seldom long-lasting. We describe a case of IBM associated with endometrial carcinoma that also demonstrated a unique response to steroids alone which persisted despite cancer relapse. The factors that are associated with a response of IBM to steroids are discussed. An atypical, steroid-responsive form of the disease is delineated.

KW - Atypical

KW - Endometrial carcinoma

KW - Inclusion body myositis

KW - Steroids

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M3 - Article

C2 - 15789894

AN - SCOPUS:15844407469

SN - 0392-856X

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JO - Clinical and Experimental Rheumatology

JF - Clinical and Experimental Rheumatology

IS - 1

ER -

Steroid-responsive inclusion body myositis associated with endometrial cancer

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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