Speckle-tracking echocardiography with novel imaging technique of higher frame rate

Kana Fujikura, Mohammed Makkiya, Muhammad Farooq, Yun Xing, Wayne Humphrey, Mohammad Hashim Mustehsan, Mario J. Garcia, Cynthia C. Taub

Research output: Contribution to journalArticlepeer-review

5 Scopus citations


Background: The accuracy of speckle-tracking echocardiography (STE) depends on temporal resolution. The goal of this study was to demonstrate the feasibility of relatively high frame rate (rHi-FR) (~200 fps) for STE. Methods: In this prospective study, echocardiographic images were acquired using clinical scanners on patients with normal left ventricular systolic function using rHi-FR and conventional frame rate (Reg-FR) (~50 FPS). GLS values were evaluated on apical 4-, 2-and 3-chamber images acquired in both rHi-FR and Reg-FR. Inter-observer and intra-observer variabilities were assessed in rHi-FR and Reg-FR. Results: There were 143 echocardiograms evaluated in this study. The frame rate of rHi-FR was 190 ± 25 and Reg-FR was 50 ± 3, and the heart rate was 71 ± 13. Absolute strain values measured in rHi-FR were significantly higher than those measured in Reg-FR (all p < 0.001). Inter-observer and intra-observer correlations were strong in both rHi-FR and Reg-FR. Conclusions: We demonstrated that absolute strain values were significantly higher using rHi-FR when compared with Reg-FR. It is plausible that higher temporal resolution enabled the measurement of myocardial strain at desired time point. Further investigations are necessary to evaluate the value of rHi-FR to assess myocardial strain in the setting of tachycardia.

Original languageEnglish (US)
Article number2095
JournalJournal of Clinical Medicine
Issue number10
StatePublished - May 2021


  • Echocardiography
  • Frame rate
  • Global longitudinal strain
  • Left ventricle
  • Speckle-tracking

ASJC Scopus subject areas

  • Medicine(all)


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