Sparing of the onufrowicz nucleus in sacral anterior horn lesions

Makoto Iwata, Asao Hirano

Research output: Contribution to journalArticlepeer-review

60 Scopus citations


Sacral anterior horns were examined with special reference to the Onufrowicz nucleus in 3 patients with Werdnig‐Hoffman disease, 2 with healed anterior poliomyelitis, and 1 who had undergone amputation of both legs above the knee. None of these patients showed symptoms of either urethral or anal sphincter disturbances. The Onufrowicz nucleus of the second sacral anterior horn appeared normal in all the patients examined, though the lateral portion of that horn and the medial nuclear group of the third sacral segment were frequently involved. These findings support the view that the Onufrowicz nucleus may be innervating the external sphincter muscle of the urethra and the anus.

Original languageEnglish (US)
Pages (from-to)245-249
Number of pages5
JournalAnnals of Neurology
Issue number3
StatePublished - Sep 1978
Externally publishedYes

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology


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