SOS induction by stabilized topoisomerase IA cleavage complex occurs via the RecBCD pathway

Jeanette H. Sutherland; Bokun Cheng; I. Fen Liu; Yuk Ching Tse-Dinh

doi:10.1128/JB.01674-07

SOS induction by stabilized topoisomerase IA cleavage complex occurs via the RecBCD pathway

Jeanette H. Sutherland
, Bokun Cheng
, I. Fen Liu
, Yuk Ching Tse-Dinh

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Abstract

Accumulation of mutant topoisomerase I cleavage complex can lead to SOS induction and cell death in Escherichia coli. The single-stranded break associated with mutant topoisomerase I cleavage complex is converted to double-stranded break, which then is processed by the RecBCD pathway, followed by association of RecA with the single-stranded DNA.

Original language	English (US)
Pages (from-to)	3399-3403
Number of pages	5
Journal	Journal of Bacteriology
Volume	190
Issue number	9
DOIs	https://doi.org/10.1128/JB.01674-07
State	Published - May 2008
Externally published	Yes

ASJC Scopus subject areas

Microbiology
Molecular Biology

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10.1128/JB.01674-07

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title = "SOS induction by stabilized topoisomerase IA cleavage complex occurs via the RecBCD pathway",

abstract = "Accumulation of mutant topoisomerase I cleavage complex can lead to SOS induction and cell death in Escherichia coli. The single-stranded break associated with mutant topoisomerase I cleavage complex is converted to double-stranded break, which then is processed by the RecBCD pathway, followed by association of RecA with the single-stranded DNA.",

author = "Sutherland, \{Jeanette H.\} and Bokun Cheng and Liu, \{I. Fen\} and Tse-Dinh, \{Yuk Ching\}",

year = "2008",

month = may,

doi = "10.1128/JB.01674-07",

language = "English (US)",

volume = "190",

pages = "3399--3403",

journal = "Journal of Bacteriology",

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publisher = "American Society for Microbiology",

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T1 - SOS induction by stabilized topoisomerase IA cleavage complex occurs via the RecBCD pathway

AU - Sutherland, Jeanette H.

AU - Cheng, Bokun

AU - Liu, I. Fen

AU - Tse-Dinh, Yuk Ching

PY - 2008/5

Y1 - 2008/5

N2 - Accumulation of mutant topoisomerase I cleavage complex can lead to SOS induction and cell death in Escherichia coli. The single-stranded break associated with mutant topoisomerase I cleavage complex is converted to double-stranded break, which then is processed by the RecBCD pathway, followed by association of RecA with the single-stranded DNA.

AB - Accumulation of mutant topoisomerase I cleavage complex can lead to SOS induction and cell death in Escherichia coli. The single-stranded break associated with mutant topoisomerase I cleavage complex is converted to double-stranded break, which then is processed by the RecBCD pathway, followed by association of RecA with the single-stranded DNA.

UR - https://www.scopus.com/pages/publications/42549102784

UR - https://www.scopus.com/pages/publications/42549102784#tab=citedBy

U2 - 10.1128/JB.01674-07

DO - 10.1128/JB.01674-07

M3 - Article

C2 - 18310346

AN - SCOPUS:42549102784

SN - 0021-9193

VL - 190

SP - 3399

EP - 3403

JO - Journal of Bacteriology

JF - Journal of Bacteriology

IS - 9

ER -

SOS induction by stabilized topoisomerase IA cleavage complex occurs via the RecBCD pathway

Abstract

ASJC Scopus subject areas

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