Small Intestinal Lymphoma in Three Patients with Acquired Immune Deficiency Syndrome

J. J. Steinberg, Nancy Bridges, Helen D. Feiner, Quentin Valensi

Research output: Contribution to journalArticlepeer-review

35 Scopus citations


Three cases of small bowel lymphoma in young homosexual men are presented. All three had acquired immune deficiency syndrome as demonstrated by demography, sexual history, cachexia, opportunistic infections by Cytomegalovirus, Pneumocystis carinii, atypical Mycobacterium, Candida, and/or evidence of immune deficiency, such as skin test anergy, lymphopenia, inversion of T‐helper/T‐suppressor ratio, and diminished lymphocyte response to either phytohemmaglutinin or pokeweed mitogen. All had peripheral and/or abdominal lymphadenopathy, and gastrointestinal symptoms, e.g., diarrhea, spasms, constipation, and oral candidiasis. The diagnosis of lymphoma was made at laparotomy in all cases. All three had complete removal of localized tumor (stage Ie or IIe), yet died within 6 months of surgery and/or chemotherapy. Thus gastrointestinal complaints may not always be related to “gay bowel” syndrome, or other infectious diseases in patients with acquired immune deficiency syndrome. Small intestinal lymphoma should be added to the list of neoplasms to which this group is susceptible.

Original languageEnglish (US)
Pages (from-to)21-26
Number of pages6
JournalThe American Journal of Gastroenterology
Issue number1
StatePublished - Jan 1985

ASJC Scopus subject areas

  • Hepatology
  • Gastroenterology


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