Sleep and Anesthesia: The Shared Circuit Hypothesis Has Been Put to Bed

Matthias Eikermann; Oluwaseun Akeju; Nancy L. Chamberlin

doi:10.1016/j.cub.2020.01.057

Sleep and Anesthesia: The Shared Circuit Hypothesis Has Been Put to Bed

Matthias Eikermann, Oluwaseun Akeju, Nancy L. Chamberlin

Research output: Contribution to journal › Comment/debate › peer-review

5 Scopus citations

Abstract

Acute activation of genetically defined sleep-promoting neurons in the preoptic hypothalamus does not facilitate anesthesia. This finding supports the notion that a mechanistic overlap between sleep and anesthesia does not explain the anesthetized brain.

Original language	English (US)
Pages (from-to)	R219-R221
Journal	Current Biology
Volume	30
Issue number	5
DOIs	https://doi.org/10.1016/j.cub.2020.01.057
State	Published - Mar 9 2020
Externally published	Yes

ASJC Scopus subject areas

Neuroscience(all)
Biochemistry, Genetics and Molecular Biology(all)
Agricultural and Biological Sciences(all)

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10.1016/j.cub.2020.01.057

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title = "Sleep and Anesthesia: The Shared Circuit Hypothesis Has Been Put to Bed",

abstract = "Acute activation of genetically defined sleep-promoting neurons in the preoptic hypothalamus does not facilitate anesthesia. This finding supports the notion that a mechanistic overlap between sleep and anesthesia does not explain the anesthetized brain.",

author = "Matthias Eikermann and Oluwaseun Akeju and Chamberlin, {Nancy L.}",

note = "Publisher Copyright: {\textcopyright} 2020 Elsevier Ltd",

year = "2020",

month = mar,

day = "9",

doi = "10.1016/j.cub.2020.01.057",

language = "English (US)",

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TY - JOUR

T1 - Sleep and Anesthesia

T2 - The Shared Circuit Hypothesis Has Been Put to Bed

AU - Eikermann, Matthias

AU - Akeju, Oluwaseun

AU - Chamberlin, Nancy L.

PY - 2020/3/9

Y1 - 2020/3/9

N2 - Acute activation of genetically defined sleep-promoting neurons in the preoptic hypothalamus does not facilitate anesthesia. This finding supports the notion that a mechanistic overlap between sleep and anesthesia does not explain the anesthetized brain.

AB - Acute activation of genetically defined sleep-promoting neurons in the preoptic hypothalamus does not facilitate anesthesia. This finding supports the notion that a mechanistic overlap between sleep and anesthesia does not explain the anesthetized brain.

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U2 - 10.1016/j.cub.2020.01.057

DO - 10.1016/j.cub.2020.01.057

M3 - Comment/debate

C2 - 32155424

AN - SCOPUS:85080867688

SN - 0960-9822

VL - 30

SP - R219-R221

JO - Current Biology

JF - Current Biology

IS - 5

ER -

Sleep and Anesthesia: The Shared Circuit Hypothesis Has Been Put to Bed

Abstract

ASJC Scopus subject areas

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