Single Monoclonal Antibodies Should Not Be Used for COVID-19 Therapy: A Call for Antiviral Stewardship

Arturo Casadevall; Daniele Focosi; Liise Anne Pirofski; Shmuel Shoham

doi:10.1093/cid/ciae408

Single Monoclonal Antibodies Should Not Be Used for COVID-19 Therapy: A Call for Antiviral Stewardship

Arturo Casadevall
, Daniele Focosi
, Liise Anne Pirofski
, Shmuel Shoham

Medicine

Research output: Contribution to journal › Short survey › peer-review

5 Scopus citations

Abstract

The COVID-19 pandemic witnessed the greatest deployment of monoclonal antibody (mAb) therapies for an infectious disease, but all were defeated by SARS-CoV-2 evolution. As new mAbs are developed, the infectious disease community needs stewardship practices to reduce emergence of resistance.

Original language	English (US)
Pages (from-to)	1404-1407
Number of pages	4
Journal	Clinical Infectious Diseases
Volume	79
Issue number	6
DOIs	https://doi.org/10.1093/cid/ciae408
State	Published - Dec 15 2024

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

COVID-19
SARS-CoV-2
monoclonal antibody
resistance
variants

ASJC Scopus subject areas

Microbiology (medical)
Infectious Diseases

Access to Document

10.1093/cid/ciae408

Cite this

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title = "Single Monoclonal Antibodies Should Not Be Used for COVID-19 Therapy: A Call for Antiviral Stewardship",

abstract = "The COVID-19 pandemic witnessed the greatest deployment of monoclonal antibody (mAb) therapies for an infectious disease, but all were defeated by SARS-CoV-2 evolution. As new mAbs are developed, the infectious disease community needs stewardship practices to reduce emergence of resistance.",

keywords = "COVID-19, SARS-CoV-2, monoclonal antibody, resistance, variants",

author = "Arturo Casadevall and Daniele Focosi and Pirofski, \{Liise Anne\} and Shmuel Shoham",

note = "Publisher Copyright: {\textcopyright} 2024 The Author(s).",

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language = "English (US)",

volume = "79",

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T1 - Single Monoclonal Antibodies Should Not Be Used for COVID-19 Therapy

T2 - A Call for Antiviral Stewardship

AU - Casadevall, Arturo

AU - Focosi, Daniele

AU - Pirofski, Liise Anne

AU - Shoham, Shmuel

PY - 2024/12/15

Y1 - 2024/12/15

N2 - The COVID-19 pandemic witnessed the greatest deployment of monoclonal antibody (mAb) therapies for an infectious disease, but all were defeated by SARS-CoV-2 evolution. As new mAbs are developed, the infectious disease community needs stewardship practices to reduce emergence of resistance.

AB - The COVID-19 pandemic witnessed the greatest deployment of monoclonal antibody (mAb) therapies for an infectious disease, but all were defeated by SARS-CoV-2 evolution. As new mAbs are developed, the infectious disease community needs stewardship practices to reduce emergence of resistance.

KW - COVID-19

KW - SARS-CoV-2

KW - monoclonal antibody

KW - resistance

KW - variants

UR - https://www.scopus.com/pages/publications/85212542683

UR - https://www.scopus.com/pages/publications/85212542683#tab=citedBy

U2 - 10.1093/cid/ciae408

DO - 10.1093/cid/ciae408

M3 - Short survey

C2 - 39115342

AN - SCOPUS:85212542683

SN - 1058-4838

VL - 79

SP - 1404

EP - 1407

JO - Clinical Infectious Diseases

JF - Clinical Infectious Diseases

IS - 6

ER -

Single Monoclonal Antibodies Should Not Be Used for COVID-19 Therapy: A Call for Antiviral Stewardship

Abstract

UN SDGs

Keywords

ASJC Scopus subject areas

Access to Document

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