Sickle cell disease and plumbism in children

Magimairajan Issaivanan, Rafat Ahmed, Monica Shekher, Debra Esernio-Jenssen, Deepa Manwani

Research output: Contribution to journalArticlepeer-review

12 Scopus citations


Childhood lead poisoning is common, affects multiple organs and is preventable. Co-existence of plumbism and sickle cell disease (SCD) is uncommon, with major overlap in signs and symptoms. We describe a patient with SCD and plumbism. Dysfunctional eating patterns may cause ingestion and increased absorption of lead in these patients. Routine screening for pica and other dysfunctionaleatinghabits with appropriatebehavioralinterventions is emphasized. Annual screening for lead in patients with SCD of all ages (1-21years) and supplementation of micronutrients like zinc and iron in deficient cases may help prevent plumbism in these patients.

Original languageEnglish (US)
Pages (from-to)653-656
Number of pages4
JournalPediatric Blood and Cancer
Issue number5
StatePublished - May 1 2009


  • Blood lead levels
  • Dysfunctional eating patterns
  • Lead encephalopathy
  • Lead neuropathy
  • Pica
  • Sickle cell disease
  • Vaso-occlusive crisis

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Hematology
  • Oncology


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