Seminal megavesicle in autosomal dominant polycystic kidney disease

Beatriu Reig, Jon Blumenfeld, Stephanie Donahue, Martin R. Prince

Research output: Contribution to journalArticlepeer-review

18 Scopus citations


Retrospective analysis of 99 male autosomal dominant polycystic kidney disease (ADPKD) patients compared to an age-matched control population showed seminal vesicle ectasia > 10 mm (megavesicle) in 23% (23/99) of ADPKD patients that was not present in any controls (P<. .0001). Median (range) seminal vesicle convoluted tubule diameter in ADPKD patients was 4.2 (1.7-30) mm compared to 3.1 (1.7-6.8) mm in controls (P<0001). Discrete cysts were identified in four ADPKD patients but in none of the control population (P= 12). Seminal megavesicles may explain the infertility sometimes observed in male ADPKD patients.

Original languageEnglish (US)
Pages (from-to)289-292
Number of pages4
JournalClinical Imaging
Issue number2
StatePublished - Mar 1 2015
Externally publishedYes


  • Autosomal dominant poylcystic kidney disease
  • Cyst
  • Infertility
  • Magnetic resonance imaging
  • Seminal vesicle ectasia

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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