Seminal megavesicle in autosomal dominant polycystic kidney disease

Beatriu Reig; Jon Blumenfeld; Stephanie Donahue; Martin R. Prince

doi:10.1016/j.clinimag.2014.10.016

Seminal megavesicle in autosomal dominant polycystic kidney disease

Beatriu Reig, Jon Blumenfeld, Stephanie Donahue, Martin R. Prince

Research output: Contribution to journal › Article › peer-review

18 Scopus citations

Abstract

Retrospective analysis of 99 male autosomal dominant polycystic kidney disease (ADPKD) patients compared to an age-matched control population showed seminal vesicle ectasia > 10 mm (megavesicle) in 23% (23/99) of ADPKD patients that was not present in any controls (P<. .0001). Median (range) seminal vesicle convoluted tubule diameter in ADPKD patients was 4.2 (1.7-30) mm compared to 3.1 (1.7-6.8) mm in controls (P<0001). Discrete cysts were identified in four ADPKD patients but in none of the control population (P= 12). Seminal megavesicles may explain the infertility sometimes observed in male ADPKD patients.

Original language	English (US)
Pages (from-to)	289-292
Number of pages	4
Journal	Clinical Imaging
Volume	39
Issue number	2
DOIs	https://doi.org/10.1016/j.clinimag.2014.10.016
State	Published - Mar 1 2015
Externally published	Yes

Keywords

Autosomal dominant poylcystic kidney disease
Cyst
Infertility
Magnetic resonance imaging
Seminal vesicle ectasia

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

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10.1016/j.clinimag.2014.10.016

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title = "Seminal megavesicle in autosomal dominant polycystic kidney disease",

abstract = "Retrospective analysis of 99 male autosomal dominant polycystic kidney disease (ADPKD) patients compared to an age-matched control population showed seminal vesicle ectasia > 10 mm (megavesicle) in 23% (23/99) of ADPKD patients that was not present in any controls (P<. .0001). Median (range) seminal vesicle convoluted tubule diameter in ADPKD patients was 4.2 (1.7-30) mm compared to 3.1 (1.7-6.8) mm in controls (P<0001). Discrete cysts were identified in four ADPKD patients but in none of the control population (P= 12). Seminal megavesicles may explain the infertility sometimes observed in male ADPKD patients.",

keywords = "Autosomal dominant poylcystic kidney disease, Cyst, Infertility, Magnetic resonance imaging, Seminal vesicle ectasia",

author = "Beatriu Reig and Jon Blumenfeld and Stephanie Donahue and Prince, {Martin R.}",

note = "Funding Information: Supported in part by grant # UL1RR024143 from the National Center for Advancing Translational Sciences (NCATS), National Institutes of Health. Publisher Copyright: {\textcopyright} 2015 Elsevier Inc.",

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doi = "10.1016/j.clinimag.2014.10.016",

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AU - Reig, Beatriu

AU - Blumenfeld, Jon

AU - Donahue, Stephanie

AU - Prince, Martin R.

N1 - Funding Information: Supported in part by grant # UL1RR024143 from the National Center for Advancing Translational Sciences (NCATS), National Institutes of Health. Publisher Copyright: © 2015 Elsevier Inc.

PY - 2015/3/1

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N2 - Retrospective analysis of 99 male autosomal dominant polycystic kidney disease (ADPKD) patients compared to an age-matched control population showed seminal vesicle ectasia > 10 mm (megavesicle) in 23% (23/99) of ADPKD patients that was not present in any controls (P<. .0001). Median (range) seminal vesicle convoluted tubule diameter in ADPKD patients was 4.2 (1.7-30) mm compared to 3.1 (1.7-6.8) mm in controls (P<0001). Discrete cysts were identified in four ADPKD patients but in none of the control population (P= 12). Seminal megavesicles may explain the infertility sometimes observed in male ADPKD patients.

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KW - Autosomal dominant poylcystic kidney disease

KW - Cyst

KW - Infertility

KW - Magnetic resonance imaging

KW - Seminal vesicle ectasia

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Seminal megavesicle in autosomal dominant polycystic kidney disease

Abstract

Keywords

ASJC Scopus subject areas

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