TY - JOUR
T1 - Risk factors associated with COVID-19-induced death in patients hospitalized in intensive care units (ICUs) in a city in Southern Brazil
AU - Olak, André S.
AU - Susuki, Aline M.
AU - Kanashiro, Milena
AU - Paoliello, Monica M.B.
AU - Aschner, Michael
AU - Urbano, Mariana R.
N1 - Funding Information:
We acknowledge CAPES and Fundação Araucária for the financial support (scholarships), the City Health Secretary of Londrina for providing the data, and the “Núcleo Interdisciplinar de Gestão Pública (NIGEP) – UEL” coordinated by Professor Vera Suguihiro and Professor Saulo Fabiano Amâncio Vieira for providing the opportunity for the research.
Publisher Copyright:
© 2021 The Authors
PY - 2021/1
Y1 - 2021/1
N2 - Objectives: The aim of this research was to address risk factors associated with death after hospitalization in intensive care units (ICUs) in 728 COVID-19 patients in Londrina, the second most populated city in the State of Paraná – Brazil, between March and December 2020. Methods: Statistical analysis, including multiple logistic regression was performed to identify risk factors associated with death in these patients. Results: The results showed that age (60 years or more, O.R. = 3.13, C.I. 95% [2.02; 4.84]), days in the ICU (11 days or more, O.R. = 1.76, C.I. 95% [1.16; 2.66]), neurological diseases (O.R. = 2.15, C.I. 95% [1.07; 4.31]), pneumopathy (O.R = 2.19, C.I. 95% [1.01; 4.82]), diabetes (O.R. = 1.55, C.I. 95% [1.03; 2.32]), and kidney disease (O.R. = 2.27, C.I. 95% [1.18; 4.70]) were associated with increased risk for death from COVID-19. Conclusion: Knowing the risk factors associated with death after ICUs hospitalization is useful for identifying the most vulnerable groups, as well as for defining vaccination priorities, considering its scarcity in many parts of the world, mainly in underdeveloped countries, including Brazil.
AB - Objectives: The aim of this research was to address risk factors associated with death after hospitalization in intensive care units (ICUs) in 728 COVID-19 patients in Londrina, the second most populated city in the State of Paraná – Brazil, between March and December 2020. Methods: Statistical analysis, including multiple logistic regression was performed to identify risk factors associated with death in these patients. Results: The results showed that age (60 years or more, O.R. = 3.13, C.I. 95% [2.02; 4.84]), days in the ICU (11 days or more, O.R. = 1.76, C.I. 95% [1.16; 2.66]), neurological diseases (O.R. = 2.15, C.I. 95% [1.07; 4.31]), pneumopathy (O.R = 2.19, C.I. 95% [1.01; 4.82]), diabetes (O.R. = 1.55, C.I. 95% [1.03; 2.32]), and kidney disease (O.R. = 2.27, C.I. 95% [1.18; 4.70]) were associated with increased risk for death from COVID-19. Conclusion: Knowing the risk factors associated with death after ICUs hospitalization is useful for identifying the most vulnerable groups, as well as for defining vaccination priorities, considering its scarcity in many parts of the world, mainly in underdeveloped countries, including Brazil.
KW - COVID-19
KW - Pandemic
KW - Risk factors
KW - Statistical analysis
UR - http://www.scopus.com/inward/record.url?scp=85112274987&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85112274987&partnerID=8YFLogxK
U2 - 10.1016/j.toxrep.2021.07.020
DO - 10.1016/j.toxrep.2021.07.020
M3 - Article
AN - SCOPUS:85112274987
SN - 2214-7500
VL - 8
SP - 1565
EP - 1568
JO - Toxicology Reports
JF - Toxicology Reports
ER -
