TY - JOUR
T1 - Right ventricular outflow tract obstruction due to extrinsic compression by non-hodgkin's lymphoma
T2 - Importance of echocardiographic diagnosis and follow up
AU - Putterman, Chaim
AU - Gilon, Dan
AU - Uretzki, Gideon
AU - Bar-Ziv, Jaacov
AU - Polliack, Aaron
PY - 1992
Y1 - 1992
N2 - Acquired right ventricular outflow tract obstruction due to extrinsic compression of the pulmonary artery is a rare manifestation of non-Hodgkin's lymphoma (NHL). We report a case of a 17 year old boy who was referred for evaluation of a large anterior mediastinal mass, causing dyspnea and cough and resulting in a harsh systolic murmur. Echocardiography demonstrated compression of the pulmonary artery by the mass, with a severe pressure gradient. Biopsy revealed intermediate grade, diffuse large cell NHL. Systemic chemotherapy rapidly led to a significant decrease in the size of the mass, and virtual disappearance of the pressure gradient. In this report, the use of echocardiography for diagnosis and follow up of extracardiac tumors is reviewed. It is suggested that this technique may also be useful for the routine staging of mediastinal lymphomas because of the potential consequences of clinically undetectable hemodynamic compromise.
AB - Acquired right ventricular outflow tract obstruction due to extrinsic compression of the pulmonary artery is a rare manifestation of non-Hodgkin's lymphoma (NHL). We report a case of a 17 year old boy who was referred for evaluation of a large anterior mediastinal mass, causing dyspnea and cough and resulting in a harsh systolic murmur. Echocardiography demonstrated compression of the pulmonary artery by the mass, with a severe pressure gradient. Biopsy revealed intermediate grade, diffuse large cell NHL. Systemic chemotherapy rapidly led to a significant decrease in the size of the mass, and virtual disappearance of the pressure gradient. In this report, the use of echocardiography for diagnosis and follow up of extracardiac tumors is reviewed. It is suggested that this technique may also be useful for the routine staging of mediastinal lymphomas because of the potential consequences of clinically undetectable hemodynamic compromise.
KW - Echocardiography
KW - Mediastinal mass
KW - Non-Hodgkin's Lymphoma
KW - Pulmonic stenosis
KW - Right ventricular outflow tract obstruction
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U2 - 10.3109/10428199209053625
DO - 10.3109/10428199209053625
M3 - Article
C2 - 1282429
AN - SCOPUS:0026684178
SN - 1042-8194
VL - 7
SP - 211
EP - 215
JO - Leukemia and Lymphoma
JF - Leukemia and Lymphoma
IS - 3
ER -