Rhino-sinus involvement in children with obstructive sleep apnea syndrome.

Raanan Arens, Sanghun Sin, Seth Willen, John Bent, Sanjay R. Parikh, Katherine Freeman, David M. Wootton, Joseph M. McDonough, Keivan Shifteh

Research output: Contribution to journalArticlepeer-review

23 Scopus citations


Obstructive sleep apnea syndrome (OSAS) is commonly associated with adenotonsillar hypertrophy. We hypothesized that respiratory perturbations extend to other regions of the upper respiratory tract in such children, particularly to rhino-sinus regions. A prospective case control study using Magnetic Resonance Imaging (MRI) of the upper airway and surrounding tissues of OSAS and controls. Magnetic resonance imaging was used to evaluate radiographic changes within the: paranasal sinuses, middle ear and mastoid air cells, and the nasal passages. We studied 54 OSAS (age 5.7 ± 3.0 years) and 54 controls (age 6.2 ± 2.0 years, P= NS). Children with OSAS had significantly more opacification of: maxillary sinuses (P< 0.05), sphenoid sinuses (P< 0.01), and mastoid air cells (P< 0.01). They also had significantly more: middle ear effusions, (P < 0.001), prominence of inferior nasal turbinate(s) (P< 0.05), and deviation of the nasal septum (P< 0.05). Childhood OSAS is associated with a wide range of upper respiratory tract perturbations and is not limited to adenoid and tonsillar hypertrophy.

Original languageEnglish (US)
Pages (from-to)993-998
Number of pages6
JournalPediatric pulmonology
Issue number10
StatePublished - Oct 2010

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Pulmonary and Respiratory Medicine


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