Respiratory Muscle Dysfunction in Hereditary Motor Sensory Neuropathy, Type I

Peter Q. Eichacker, Alfred Spiro, Michael Sherman, Eliot Lazar, Joseph Reichel, Fran Dodick

Research output: Contribution to journalArticlepeer-review

28 Scopus citations


Pulmonary function tests were performed on ten patients who were shown to have hereditary motor sensory neuropathy, type I. Mean values for spirometry, static lung volumes, and diffusion capacity were all greater than 80% of the predicted normal values for the group. In contrast, both inspiratory and expiratory muscle testing showed substantial reductions in function for the group. These abnormalities have not previously been reported, and they may be important in the management of these patients and in patients with other neuromuscular diseases.

Original languageEnglish (US)
Pages (from-to)1739-1740
Number of pages2
JournalArchives of internal medicine
Issue number8
StatePublished - Aug 1988

ASJC Scopus subject areas

  • Internal Medicine


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