Respiratory adverse events associated with diazepam rectal gel

John M. Pellock, Shlomo Shinnar

Research output: Contribution to journalArticlepeer-review

18 Scopus citations


The authors reviewed respiratory adverse events and deaths spontaneously reported to Xcel Pharmaceuticals associated with diazepam rectal gel. Over 2 million doses have been prescribed. The authors identified nine respiratory adverse events and three deaths. The respiratory events associated with prolonged seizures had a good outcome. The deaths occurred in the context of a prolonged seizure and respiratory depression was not the main symptom. When used as recommended, diazepam rectal gel has a low rate of serious morbidity or mortality.

Original languageEnglish (US)
Pages (from-to)1768-1770
Number of pages3
Issue number10
StatePublished - May 24 2005

ASJC Scopus subject areas

  • Clinical Neurology


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