Renal Medullary Carcinoma with an Aggressive Clinical Course: A Case Report and Review of the Literature

Madhumati R. Kalavar; Sami Ali; Damoun Safarpour; Saroj Davi Kunnakkat

doi:10.1159/000455007

Renal Medullary Carcinoma with an Aggressive Clinical Course: A Case Report and Review of the Literature

Madhumati R. Kalavar, Sami Ali, Damoun Safarpour, Saroj Davi Kunnakkat

Research output: Contribution to journal › Review article › peer-review

2 Scopus citations

Abstract

Renal medullary carcinoma (RMC) is a rare, yet aggressive malignancy of the kidney that is found predominantly in young patients with African descent and sickle cell hemoglobinopathies and most specifically sickle cell trait. Due to its aggressive nature, most cases have metastasis or local invasion at the time of diagnosis. Prognosis is extremely poor with survival less than 1 year after diagnosis. Here we present a case of metastatic RMC in a 29-year-old African female. Despite chemotherapy with cisplatin, gemcitabine, and paclitaxel, and initial shrinkage of the tumor, the patient died 5 months after diagnosis.

Original language	English (US)
Pages (from-to)	1-7
Number of pages	7
Journal	Case Reports in Oncology
Volume	10
Issue number	1
DOIs	https://doi.org/10.1159/000455007
State	Published - Jan 6 2017
Externally published	Yes

Keywords

African descent
Kidney tumor
Metastasis
Renal medullary carcinoma
Sickle cell anemia
Sickle cell trait

ASJC Scopus subject areas

Oncology

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10.1159/000455007

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abstract = "Renal medullary carcinoma (RMC) is a rare, yet aggressive malignancy of the kidney that is found predominantly in young patients with African descent and sickle cell hemoglobinopathies and most specifically sickle cell trait. Due to its aggressive nature, most cases have metastasis or local invasion at the time of diagnosis. Prognosis is extremely poor with survival less than 1 year after diagnosis. Here we present a case of metastatic RMC in a 29-year-old African female. Despite chemotherapy with cisplatin, gemcitabine, and paclitaxel, and initial shrinkage of the tumor, the patient died 5 months after diagnosis.",

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AU - Ali, Sami

AU - Safarpour, Damoun

AU - Kunnakkat, Saroj Davi

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N2 - Renal medullary carcinoma (RMC) is a rare, yet aggressive malignancy of the kidney that is found predominantly in young patients with African descent and sickle cell hemoglobinopathies and most specifically sickle cell trait. Due to its aggressive nature, most cases have metastasis or local invasion at the time of diagnosis. Prognosis is extremely poor with survival less than 1 year after diagnosis. Here we present a case of metastatic RMC in a 29-year-old African female. Despite chemotherapy with cisplatin, gemcitabine, and paclitaxel, and initial shrinkage of the tumor, the patient died 5 months after diagnosis.

AB - Renal medullary carcinoma (RMC) is a rare, yet aggressive malignancy of the kidney that is found predominantly in young patients with African descent and sickle cell hemoglobinopathies and most specifically sickle cell trait. Due to its aggressive nature, most cases have metastasis or local invasion at the time of diagnosis. Prognosis is extremely poor with survival less than 1 year after diagnosis. Here we present a case of metastatic RMC in a 29-year-old African female. Despite chemotherapy with cisplatin, gemcitabine, and paclitaxel, and initial shrinkage of the tumor, the patient died 5 months after diagnosis.

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KW - Metastasis

KW - Renal medullary carcinoma

KW - Sickle cell anemia

KW - Sickle cell trait

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Renal Medullary Carcinoma with an Aggressive Clinical Course: A Case Report and Review of the Literature

Abstract

Keywords

ASJC Scopus subject areas

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