Relationship between whole blood serotonin and repetitive behaviors in autism

Alexander Kolevzon; Jeffrey H. Newcorn; Lauren Kryzak; William Chaplin; Dryden Watner; Eric Hollander; Christopher J. Smith; Edwin H. Cook; Jeremy M. Silverman

doi:10.1016/j.psychres.2009.02.008

Relationship between whole blood serotonin and repetitive behaviors in autism

Alexander Kolevzon
, Jeffrey H. Newcorn
, Lauren Kryzak
, William Chaplin
, Dryden Watner
, Eric Hollander
, Christopher J. Smith
, Edwin H. Cook
, Jeremy M. Silverman

Psychiatry and Behavioral Sciences

Research output: Contribution to journal › Article › peer-review

36 Scopus citations

Abstract

This study was conducted to examine the relationship between whole blood serotonin level and behavioral symptoms in 78 subjects with autism. No significant associations were found between serotonin level and the primary behavioral outcome measures. However, a significant inverse relationship between serotonin level and self-injury was demonstrated.

Original language	English (US)
Pages (from-to)	274-276
Number of pages	3
Journal	Psychiatry Research
Volume	175
Issue number	3
DOIs	https://doi.org/10.1016/j.psychres.2009.02.008
State	Published - Feb 28 2010

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Aggression
Autism
Repetitive behavior
Self-injury
Serotonin

ASJC Scopus subject areas

Psychiatry and Mental health
Biological Psychiatry

Access to Document

10.1016/j.psychres.2009.02.008

Cite this

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title = "Relationship between whole blood serotonin and repetitive behaviors in autism",

abstract = "This study was conducted to examine the relationship between whole blood serotonin level and behavioral symptoms in 78 subjects with autism. No significant associations were found between serotonin level and the primary behavioral outcome measures. However, a significant inverse relationship between serotonin level and self-injury was demonstrated.",

keywords = "Aggression, Autism, Repetitive behavior, Self-injury, Serotonin",

author = "Alexander Kolevzon and Newcorn, \{Jeffrey H.\} and Lauren Kryzak and William Chaplin and Dryden Watner and Eric Hollander and Smith, \{Christopher J.\} and Cook, \{Edwin H.\} and Silverman, \{Jeremy M.\}",

note = "Funding Information: This work was supported in part by the AACAP/Eli Lily Young Investigator Award (Dr. Kolevzon), the Seaver Autism Center (Drs. Hollander and Silverman), and the National Institute of Mental Health through a STAART grant (U54 MH 066673). Dr. Hollander also receives support from the Orphan Products Division of the Food and Drug Administration grant \#FD-R-001520-01-03, and an investigator initiated research grant from Lilly Research Labs. Dr. Cook receives support from the Jean Young and Walden W. Shaw Foundation and The Daniel X. \& Mary Freedman Foundation for Academic Psychiatry.",

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doi = "10.1016/j.psychres.2009.02.008",

language = "English (US)",

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T1 - Relationship between whole blood serotonin and repetitive behaviors in autism

AU - Kolevzon, Alexander

AU - Newcorn, Jeffrey H.

AU - Kryzak, Lauren

AU - Chaplin, William

AU - Watner, Dryden

AU - Hollander, Eric

AU - Smith, Christopher J.

AU - Cook, Edwin H.

AU - Silverman, Jeremy M.

N1 - Funding Information: This work was supported in part by the AACAP/Eli Lily Young Investigator Award (Dr. Kolevzon), the Seaver Autism Center (Drs. Hollander and Silverman), and the National Institute of Mental Health through a STAART grant (U54 MH 066673). Dr. Hollander also receives support from the Orphan Products Division of the Food and Drug Administration grant #FD-R-001520-01-03, and an investigator initiated research grant from Lilly Research Labs. Dr. Cook receives support from the Jean Young and Walden W. Shaw Foundation and The Daniel X. & Mary Freedman Foundation for Academic Psychiatry.

PY - 2010/2/28

Y1 - 2010/2/28

N2 - This study was conducted to examine the relationship between whole blood serotonin level and behavioral symptoms in 78 subjects with autism. No significant associations were found between serotonin level and the primary behavioral outcome measures. However, a significant inverse relationship between serotonin level and self-injury was demonstrated.

AB - This study was conducted to examine the relationship between whole blood serotonin level and behavioral symptoms in 78 subjects with autism. No significant associations were found between serotonin level and the primary behavioral outcome measures. However, a significant inverse relationship between serotonin level and self-injury was demonstrated.

KW - Aggression

KW - Autism

KW - Repetitive behavior

KW - Self-injury

KW - Serotonin

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DO - 10.1016/j.psychres.2009.02.008

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Relationship between whole blood serotonin and repetitive behaviors in autism

Abstract

UN SDGs

Keywords

ASJC Scopus subject areas

Access to Document

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