Randomized Controlled Trials in Neuroendocrine Tumors

John C. McAuliffe, Edward M. Wolin

Research output: Contribution to journalReview articlepeer-review

2 Scopus citations


Understanding of neuroendocrine tumors has increased greatly in the last 2 decades. Along with this, the prevalence of neuroendocrine tumors has increased because of the ubiquitous use of cross-sectional imaging, improved endoscopic screening, and the indolent nature of the disease. Up to 35% of patients have symptoms at the time of diagnosis, whereas the others have occult disease. Neuroendocrine tumors are a diverse group of malignancies with unique clinical courses. This article critically reviews the most important randomized controlled trials for neuroendocrine tumors and introduces a few awaiting completion.

Original languageEnglish (US)
Pages (from-to)751-765
Number of pages15
JournalSurgical Oncology Clinics of North America
Issue number4
StatePublished - Oct 2017


  • Carcinoid
  • Clinical trial
  • Neuroendocrine tumor
  • Somatostatin

ASJC Scopus subject areas

  • Surgery
  • Oncology


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