Puzzles, promises and a cure for ageing

Jan Vijg; Judith Campisi

doi:10.1038/nature07216

Puzzles, promises and a cure for ageing

Jan Vijg
, Judith Campisi

Genetics

Research output: Contribution to journal › Review article › peer-review

332 Scopus citations

Abstract

Recent discoveries in the science of ageing indicate that lifespan in model organisms such as yeast, nematodes, flies and mice is plastic and can be manipulated by genetic, nutritional or pharmacological intervention. A better understanding of the targets of such interventions, as well as the proximate causes of ageing-related degeneration and disease, is essential before we can evaluate if abrogation of human senescence is a realistic prospect.

Original language	English (US)
Pages (from-to)	1065-1071
Number of pages	7
Journal	Nature
Volume	454
Issue number	7208
DOIs	https://doi.org/10.1038/nature07216
State	Published - Aug 28 2008

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

ASJC Scopus subject areas

General

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10.1038/nature07216

Cite this

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author = "Jan Vijg and Judith Campisi",

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N2 - Recent discoveries in the science of ageing indicate that lifespan in model organisms such as yeast, nematodes, flies and mice is plastic and can be manipulated by genetic, nutritional or pharmacological intervention. A better understanding of the targets of such interventions, as well as the proximate causes of ageing-related degeneration and disease, is essential before we can evaluate if abrogation of human senescence is a realistic prospect.

AB - Recent discoveries in the science of ageing indicate that lifespan in model organisms such as yeast, nematodes, flies and mice is plastic and can be manipulated by genetic, nutritional or pharmacological intervention. A better understanding of the targets of such interventions, as well as the proximate causes of ageing-related degeneration and disease, is essential before we can evaluate if abrogation of human senescence is a realistic prospect.

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Puzzles, promises and a cure for ageing

Abstract

UN SDGs

ASJC Scopus subject areas

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