Prevention and management of catheter-related infection in hemodialysis patients

Charmaine E. Lok; Michele H. Mokrzycki

doi:10.1038/ki.2010.471

Prevention and management of catheter-related infection in hemodialysis patients

Charmaine E. Lok, Michele H. Mokrzycki

Medicine

Research output: Contribution to journal › Review article › peer-review

179 Scopus citations

Abstract

Central venous catheter-related infections have been associated with high morbidity, mortality, and costs. Catheter use in chronic hemodialysis patients has been recognized as distinct from other patient populations who require central venous access, leading to recent adaptations in guidelines-recommended diagnosis for catheter-related bacteremia (CRB). This review will discuss the epidemiology and pathogenesis of hemodialysis CRB, in addition to a focus on interventions that have favorably affected CRB outcomes. These include: (1) the use of prophylactic topical antimicrobial ointments at the catheter exit site, (2) the use of prophylactic catheter locking solutions for the prevention of CRB, (3) strategies for management of the catheter in CRB, and (4) the use of vascular access managers and quality initiative programs.

Original language	English (US)
Pages (from-to)	587-598
Number of pages	12
Journal	Kidney international
Volume	79
Issue number	6
DOIs	https://doi.org/10.1038/ki.2010.471
State	Published - Mar 2011

Keywords

Staphylococcus aureus
hemodialysis access
sepsis
slime and virulence factors
vascular access

ASJC Scopus subject areas

Nephrology

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10.1038/ki.2010.471

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AB - Central venous catheter-related infections have been associated with high morbidity, mortality, and costs. Catheter use in chronic hemodialysis patients has been recognized as distinct from other patient populations who require central venous access, leading to recent adaptations in guidelines-recommended diagnosis for catheter-related bacteremia (CRB). This review will discuss the epidemiology and pathogenesis of hemodialysis CRB, in addition to a focus on interventions that have favorably affected CRB outcomes. These include: (1) the use of prophylactic topical antimicrobial ointments at the catheter exit site, (2) the use of prophylactic catheter locking solutions for the prevention of CRB, (3) strategies for management of the catheter in CRB, and (4) the use of vascular access managers and quality initiative programs.

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Prevention and management of catheter-related infection in hemodialysis patients

Abstract

Keywords

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