Prevalence and trends of isolated systolic hypertension among untreated adults in the United States

Xuefeng Liu, Carlos J. Rodriguez, Kesheng Wang

Research output: Contribution to journalArticlepeer-review

52 Scopus citations


The prevalence and long-term trends of isolated systolic hypertension (ISH) among untreated adults have not been reported. Data from 24,653 participants aged ≥18 years were selected from the National Health and Nutrition Examination Survey 1999-2010. The prevalence and 95% confidence intervals (CIs) of untreated ISH were estimated by conducting the independent survey t-test. The prevalence of untreated ISH was 9.4% and decreased from 10.3% in 1999-2004 to 8.5% in 2005-2010 (P =.00248). Old persons, females, and non-Hispanic blacks had higher prevalence of untreated ISH. Compared with 1999-2004, the prevalence of untreated ISH in 2005-2010 decreased among older (33.6%; 95% CI, 30.9%-36.3% vs. 25.1%; 95% CI, 22.7%-27.5%) and female individuals (8.3%; 95% CI, 7.5-9.2% vs. 11.4%; 95% CI, 10.4-12.3%). The stratified prevalence of untreated ISH declined in 2005-2010 (vs. 1999-2004) for older non-Hispanic whites (24.6% vs. 32.8%; P <.0001) and blacks (27.7% vs. 40.8%; P =.0013), non-Hispanic white females (7.5% vs. 10.8%; P <.0001), older individuals with higher education (21.0% vs. 30.6%; P =.0024), and females with lower education (10.1% vs. 13.1%; P =.006). Untreated ISH is more prevalent in older adults and females. Significant decreases in untreated ISH prevalence over time among these groups suggest that public health measures and/or treatment patterns are trending in the right direction.

Original languageEnglish (US)
Pages (from-to)197-205
Number of pages9
JournalJournal of the American Society of Hypertension
Issue number3
StatePublished - Mar 1 2015
Externally publishedYes


  • Blood pressure
  • hypertension
  • isolated systolic hypertension
  • prevalence

ASJC Scopus subject areas

  • Internal Medicine
  • Cardiology and Cardiovascular Medicine


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