Preparation of Polyfunctional Heterocycles Using Highly Functionalized Aminated Arylmagnesium Reagents as Versatile Scaffolds

David M. Lindsay; Wolfgang Dohle; Anne Eeg Jensen; Felix Kopp; Paul Knochel

doi:10.1021/ol025597x

Preparation of Polyfunctional Heterocycles Using Highly Functionalized Aminated Arylmagnesium Reagents as Versatile Scaffolds

David M. Lindsay, Wolfgang Dohle, Anne Eeg Jensen, Felix Kopp, Paul Knochel

Research output: Contribution to journal › Article › peer-review

62 Scopus citations

Abstract

(Equation Presented) Functionalized Grignard reagents, derived from readily available o-iodoaniline derivatives and obtained via a straightforward iodine-magnesium exchange, can be used to prepare a wide range of polyfunctional indoles, quinolines, and quinazolinones.

Original language	English (US)
Pages (from-to)	1819-1822
Number of pages	4
Journal	Organic Letters
Volume	4
Issue number	11
DOIs	https://doi.org/10.1021/ol025597x
State	Published - May 30 2002
Externally published	Yes

ASJC Scopus subject areas

Biochemistry
Physical and Theoretical Chemistry
Organic Chemistry

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title = "Preparation of Polyfunctional Heterocycles Using Highly Functionalized Aminated Arylmagnesium Reagents as Versatile Scaffolds",

abstract = "(Equation Presented) Functionalized Grignard reagents, derived from readily available o-iodoaniline derivatives and obtained via a straightforward iodine-magnesium exchange, can be used to prepare a wide range of polyfunctional indoles, quinolines, and quinazolinones.",

author = "Lindsay, {David M.} and Wolfgang Dohle and Jensen, {Anne Eeg} and Felix Kopp and Paul Knochel",

year = "2002",

month = may,

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doi = "10.1021/ol025597x",

language = "English (US)",

volume = "4",

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journal = "Organic Letters",

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T1 - Preparation of Polyfunctional Heterocycles Using Highly Functionalized Aminated Arylmagnesium Reagents as Versatile Scaffolds

AU - Lindsay, David M.

AU - Dohle, Wolfgang

AU - Jensen, Anne Eeg

AU - Kopp, Felix

AU - Knochel, Paul

PY - 2002/5/30

Y1 - 2002/5/30

N2 - (Equation Presented) Functionalized Grignard reagents, derived from readily available o-iodoaniline derivatives and obtained via a straightforward iodine-magnesium exchange, can be used to prepare a wide range of polyfunctional indoles, quinolines, and quinazolinones.

AB - (Equation Presented) Functionalized Grignard reagents, derived from readily available o-iodoaniline derivatives and obtained via a straightforward iodine-magnesium exchange, can be used to prepare a wide range of polyfunctional indoles, quinolines, and quinazolinones.

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DO - 10.1021/ol025597x

M3 - Article

C2 - 12027622

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EP - 1822

JO - Organic Letters

JF - Organic Letters

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ER -

Preparation of Polyfunctional Heterocycles Using Highly Functionalized Aminated Arylmagnesium Reagents as Versatile Scaffolds

Abstract

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