Physical activity modulating lipid metabolism in gallbladder diseases

Harshitha Shanmugam, Emilio Molina-Molina, Domenica Maria Di Palo, Maria Felicia Faienza, Agostino Di Ciaula, Gabriella Garruti, David Q.H. Wang, Piero Portincasa

Research output: Contribution to journalReview articlepeer-review

8 Scopus citations


Physical activity encompasses a series of overall benefits on cardiovascular health and metabolic disorders. Research has recently focused on the hepatobiliary tract, as an additional target of the health-related outcomes of different types of physical exercise. Here, we focus on the global features of physical activity with respect to exercise modality and intensity, and on studies linking physical activity to lipid metabolism, gallbladder diseases (gallstones, symptoms, complications and health-related quality of life), gallbladder motor-function, enterohepatic circulation of bile acids, and systemic metabolic inflammation. Additional studies need to unravel the pathophysiological mechanisms involved in both beneficial and harmful effects of physical activity in populations with different metabolic conditions.

Original languageEnglish (US)
Pages (from-to)99-110
Number of pages12
JournalJournal of Gastrointestinal and Liver Diseases
Issue number1
StatePublished - Mar 2020


  • Bile acids
  • Gallbladder disease
  • Lipids
  • Physical activity

ASJC Scopus subject areas

  • General Medicine


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