Paramecium genome survey: A pilot project

Philippe Dessen; Marek Zagulski; Robert Gromadka; Helmut Plattner; Roland Kissmehl; Eric Meyer; Mireille Bétermier; Joachim E. Schultz; Jürgen U. Linder; Ronald E. Pearlman; Ching Kung; Jim Forney; Birgit H. Satir; Judith L. Van Houten; Anne Marie Keller; Marine Froissard; Linda Sperling; Jean Cohen

doi:10.1016/S0168-9525(01)02307-1

Paramecium genome survey: A pilot project

Philippe Dessen, Marek Zagulski, Robert Gromadka, Helmut Plattner, Roland Kissmehl, Eric Meyer, Mireille Bétermier, Joachim E. Schultz, Jürgen U. Linder, Ronald E. Pearlman, Ching Kung, Jim Forney, Birgit H. Satir, Judith L. Van Houten, Anne Marie Keller, Marine Froissard, Linda Sperling, Jean Cohen

Anatomy & Structural Biology

Research output: Contribution to journal › Short survey › peer-review

61 Scopus citations

Abstract

A consortium of laboratories undertook a pilot sequencing project to gain insight into the genome of Paramecium. Plasmid-end sequencing of DNA fragments from the somatic nucleus together with similarity searches identified 722 potential protein-coding genes. High gene density and uniform small intron size make random sequencing of somatic chromosomes a cost-effective strategy for gene discovery in this organism.

Original language	English (US)
Pages (from-to)	306-308
Number of pages	3
Journal	Trends in Genetics
Volume	17
Issue number	6
DOIs	https://doi.org/10.1016/S0168-9525(01)02307-1
State	Published - Jun 1 2001

ASJC Scopus subject areas

Genetics

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Dessen, P., Zagulski, M., Gromadka, R., Plattner, H., Kissmehl, R., Meyer, E., Bétermier, M., Schultz, J. E., Linder, J. U., Pearlman, R. E., Kung, C., Forney, J., Satir, B. H., Van Houten, J. L., Keller, A. M., Froissard, M., Sperling, L., & Cohen, J. (2001). Paramecium genome survey: A pilot project. Trends in Genetics, 17(6), 306-308. https://doi.org/10.1016/S0168-9525(01)02307-1

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abstract = "A consortium of laboratories undertook a pilot sequencing project to gain insight into the genome of Paramecium. Plasmid-end sequencing of DNA fragments from the somatic nucleus together with similarity searches identified 722 potential protein-coding genes. High gene density and uniform small intron size make random sequencing of somatic chromosomes a cost-effective strategy for gene discovery in this organism.",

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doi = "10.1016/S0168-9525(01)02307-1",

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T2 - A pilot project

AU - Dessen, Philippe

AU - Zagulski, Marek

AU - Gromadka, Robert

AU - Plattner, Helmut

AU - Kissmehl, Roland

AU - Meyer, Eric

AU - Bétermier, Mireille

AU - Schultz, Joachim E.

AU - Linder, Jürgen U.

AU - Pearlman, Ronald E.

AU - Kung, Ching

AU - Forney, Jim

AU - Satir, Birgit H.

AU - Van Houten, Judith L.

AU - Keller, Anne Marie

AU - Froissard, Marine

AU - Sperling, Linda

AU - Cohen, Jean

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N2 - A consortium of laboratories undertook a pilot sequencing project to gain insight into the genome of Paramecium. Plasmid-end sequencing of DNA fragments from the somatic nucleus together with similarity searches identified 722 potential protein-coding genes. High gene density and uniform small intron size make random sequencing of somatic chromosomes a cost-effective strategy for gene discovery in this organism.

AB - A consortium of laboratories undertook a pilot sequencing project to gain insight into the genome of Paramecium. Plasmid-end sequencing of DNA fragments from the somatic nucleus together with similarity searches identified 722 potential protein-coding genes. High gene density and uniform small intron size make random sequencing of somatic chromosomes a cost-effective strategy for gene discovery in this organism.

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DO - 10.1016/S0168-9525(01)02307-1

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JO - Trends in Genetics

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Paramecium genome survey: A pilot project

Abstract

ASJC Scopus subject areas

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