TY - JOUR
T1 - Pain and medication adherence in adult cigarette smokers living with HIV
T2 - a cross-sectional observational study
AU - Willoughby, Melody
AU - Weinberger, Andrea H.
AU - Shuter, Jonathan
AU - Seng, Elizabeth K.
N1 - Funding Information:
This work was supported by the National Institute of Health [grant number R01-DA036445], [grant number R01-CA192954], [grant number R34-DA037042], [grant number K23-NS096107], and [grant number P30-AI124414]. The authors thank Alyssa Burns, Channah Esan, Brittlyn Katz Pearlman, Christine Lee, and Kate Segal for their help with data collection. The authors also thank Channah Esan for conducting literature searches. The Morisky Widget, MMAS-8, and MMAS-4 are protected by US and International Trademark and Copyright laws and applicable trade secrets statutes. Permission for use is required. A license agreement is available from: Donald E. Morisky, 294 Lindura Court, Las Vegas, NV 89138-4632; USA; dmorisky@gmail.com.
Publisher Copyright:
© 2020 Informa UK Limited, trading as Taylor & Francis Group.
PY - 2021
Y1 - 2021
N2 - The present study examines relationships between pain, mental health symptoms, and medication adherence in adult smokers living with HIV. Sixty-eight adult HIV-positive smokers taking antiretroviral medication completed a survey measuring medication adherence, mental health symptoms, and pain. The presence of pain, OR = 3.81, 95% CI (1.19, 12.14), higher pain severity, OR = 1.22, 95% CI (1.05, 1.41), and higher anxiety, OR = 1.09, 95% CI (1.03, 1.14) were associated with inferior medication adherence (MMAS-8 score <6). Anxiety mediated the relationships between presence of pain (ab =.56, BCa CI (0.05, 1.61)) and pain severity (ab =.09, BCa CI (0.01, 0.24)) and medication adherence. The results of this study suggest that pain and anxiety are factors that significantly contribute to medication nonadherence and thus are important areas of assessment by clinicians treating adult smokers living with HIV.
AB - The present study examines relationships between pain, mental health symptoms, and medication adherence in adult smokers living with HIV. Sixty-eight adult HIV-positive smokers taking antiretroviral medication completed a survey measuring medication adherence, mental health symptoms, and pain. The presence of pain, OR = 3.81, 95% CI (1.19, 12.14), higher pain severity, OR = 1.22, 95% CI (1.05, 1.41), and higher anxiety, OR = 1.09, 95% CI (1.03, 1.14) were associated with inferior medication adherence (MMAS-8 score <6). Anxiety mediated the relationships between presence of pain (ab =.56, BCa CI (0.05, 1.61)) and pain severity (ab =.09, BCa CI (0.01, 0.24)) and medication adherence. The results of this study suggest that pain and anxiety are factors that significantly contribute to medication nonadherence and thus are important areas of assessment by clinicians treating adult smokers living with HIV.
KW - HIV
KW - Medication adherence
KW - anxiety
KW - depression
KW - pain
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U2 - 10.1080/09540121.2020.1849530
DO - 10.1080/09540121.2020.1849530
M3 - Article
C2 - 33233919
AN - SCOPUS:85096557654
SN - 0954-0121
VL - 33
SP - 1422
EP - 1429
JO - AIDS Care - Psychological and Socio-Medical Aspects of AIDS/HIV
JF - AIDS Care - Psychological and Socio-Medical Aspects of AIDS/HIV
IS - 11
ER -
