Pain and medication adherence in adult cigarette smokers living with HIV: a cross-sectional observational study

Melody Willoughby, Andrea H. Weinberger, Jonathan Shuter, Elizabeth K. Seng

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

The present study examines relationships between pain, mental health symptoms, and medication adherence in adult smokers living with HIV. Sixty-eight adult HIV-positive smokers taking antiretroviral medication completed a survey measuring medication adherence, mental health symptoms, and pain. The presence of pain, OR = 3.81, 95% CI (1.19, 12.14), higher pain severity, OR = 1.22, 95% CI (1.05, 1.41), and higher anxiety, OR = 1.09, 95% CI (1.03, 1.14) were associated with inferior medication adherence (MMAS-8 score <6). Anxiety mediated the relationships between presence of pain (ab =.56, BCa CI (0.05, 1.61)) and pain severity (ab =.09, BCa CI (0.01, 0.24)) and medication adherence. The results of this study suggest that pain and anxiety are factors that significantly contribute to medication nonadherence and thus are important areas of assessment by clinicians treating adult smokers living with HIV.

Original languageEnglish (US)
Pages (from-to)1422-1429
Number of pages8
JournalAIDS Care - Psychological and Socio-Medical Aspects of AIDS/HIV
Volume33
Issue number11
DOIs
StatePublished - 2021

Keywords

  • HIV
  • Medication adherence
  • anxiety
  • depression
  • pain

ASJC Scopus subject areas

  • Health(social science)
  • Social Psychology
  • Public Health, Environmental and Occupational Health

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