Abstract
Purpose: To evaluate if elevated male body mass influences success after assisted reproductive technologies Methods: Retrospective study of 290 cycles. Results: Male body mass index greater than 25.0 kg/m2 was associated with significantly lower clinical pregnancy (53.2% vs. 33.6%). Multivariable logistic regression indicated that the likelihood of clinical pregnancy was decreased if the male partner was overweight after in vitro fertilization but not after intracytoplasmic sperm injection (odds ratios: 0.21 [0.07-0.69] vs. 0.75 [0.38-1.49], respectively) after adjustment for number of embryos transferred, sperm concentration, female age and body mass. Conclusion: In this cohort, overweight status of the male partner was independently associated with decreased likelihood of clinical pregnancy after in vitro fertilization but not after intracytoplasmic sperm injection. A detrimental impact of higher male body mass was observed after adjusting for sperm concentration, suggesting that intracytoplasmic sperm injection may overcome some obesity related impairment of sperm-egg interaction.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 539-544 |
| Number of pages | 6 |
| Journal | Journal of Assisted Reproduction and Genetics |
| Volume | 27 |
| Issue number | 9-10 |
| DOIs | |
| State | Published - Sep 2010 |
Keywords
- Assisted reproduction
- IVF/ICSI outcome
- In vitro fertilization
- Male obesity
ASJC Scopus subject areas
- Reproductive Medicine
- Genetics
- Obstetrics and Gynecology
- Developmental Biology
- Genetics(clinical)
