Ovarian development in 46,XY gonadal dysgenesis

Marcia H. Russell, Stephen S. Wachtel, Ben W. Davis, Linda T. Cahill, Erich Groos, Gary D. Niblack, Ian M. Burr

Research output: Contribution to journalArticlepeer-review


In human the XY ovary is degenerative, there being scant evidence of persistence of that organ beyond the perinatal period. Here we describe indications of functional ovarian tissue in a 17-year-old female with male karyotype, H-Y+ cellular phenotype, and some signs of the Turner syndrome. Her gonads were removed after the onset of secondary amenorrhea. Histological examination revealed a degenerative right ovary devoid of germ cells and follicles, and a left streak gonad. There was no trace of testicular development in either side.

Original languageEnglish (US)
Pages (from-to)196-199
Number of pages4
JournalHuman Genetics
Issue number2
StatePublished - Jun 1982
Externally publishedYes

ASJC Scopus subject areas

  • Genetics
  • Genetics(clinical)


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