Numb chin syndrome in ewing sarcoma

Nuno Lobo Antunes; Richard Gorlick; Elizabeth Callaja; Eric Lis

doi:10.1097/00043426-200011000-00010

Numb chin syndrome in ewing sarcoma

Nuno Lobo Antunes, Richard Gorlick, Elizabeth Callaja, Eric Lis

Pediatrics

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

The numb chin syndrome consists of unilateral hypesthesia of the chin and lower lip. In adults, it is often associated with metastatic disease to the mandible, base of the skull, or leptomeninges. In children, it has been associated with infiltration of the inferior alveolar nerve by leukemic cells. We describe two cases of numb chin syndrome in children with Ewing sarcoma. In a child with a solid tumor, this symptom seems to have an ominous meaning and should lead to the investigation of progressive skeletal involvement.

Original language	English (US)
Pages (from-to)	521-523
Number of pages	3
Journal	American Journal of Pediatric Hematology/Oncology
Volume	22
Issue number	6
DOIs	https://doi.org/10.1097/00043426-200011000-00010
State	Published - Jan 1 2000

Keywords

Ewing sarcoma
Metastases
Numb chin

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Hematology
Oncology

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10.1097/00043426-200011000-00010

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AU - Antunes, Nuno Lobo

AU - Gorlick, Richard

AU - Callaja, Elizabeth

AU - Lis, Eric

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N2 - The numb chin syndrome consists of unilateral hypesthesia of the chin and lower lip. In adults, it is often associated with metastatic disease to the mandible, base of the skull, or leptomeninges. In children, it has been associated with infiltration of the inferior alveolar nerve by leukemic cells. We describe two cases of numb chin syndrome in children with Ewing sarcoma. In a child with a solid tumor, this symptom seems to have an ominous meaning and should lead to the investigation of progressive skeletal involvement.

AB - The numb chin syndrome consists of unilateral hypesthesia of the chin and lower lip. In adults, it is often associated with metastatic disease to the mandible, base of the skull, or leptomeninges. In children, it has been associated with infiltration of the inferior alveolar nerve by leukemic cells. We describe two cases of numb chin syndrome in children with Ewing sarcoma. In a child with a solid tumor, this symptom seems to have an ominous meaning and should lead to the investigation of progressive skeletal involvement.

KW - Ewing sarcoma

KW - Metastases

KW - Numb chin

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JO - American Journal of Pediatric Hematology/Oncology

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Numb chin syndrome in ewing sarcoma

Abstract

Keywords

ASJC Scopus subject areas

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