Abstract
Purpose: To report a case of Non-Arteritic Ischemic Optic Neuropathy (NAION) in a middle-aged bodybuilder in excellent physiological condition without any signs or symptoms of vasculopathy and a history of nitric oxide supplement usage. Observations: The patient had visual acuity of 20/25 in the right eye, and 20/30 in the left eye, with a relative afferent pupillary defect and dyschromatopsia in the right eye. Visual field testing with Humphrey perimetry demonstrated an inferior altitudinal field defect OD. Fundus examination showed a small cupless disc OD with mild pallor, and a small cupless disc OS. He denied usage of sildenafil or other phosphodiesterase (PDE) inhibitor medications but frequently ingested megadoses of nitric oxide (NO) as part of his bodybuilding regimen. Conclusions: Nitric oxide supplements act through the same pharmacologic pathway as PDE inhibitors, and this case is suggestive that other vasodilating agents may be similarly associated with NAION.
Original language | English (US) |
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Pages (from-to) | 26-27 |
Number of pages | 2 |
Journal | American Journal of Ophthalmology Case Reports |
Volume | 11 |
DOIs | |
State | Published - Sep 2018 |
Keywords
- Nitric oxide
- Non-arteritic ischemic optic neuropathy
- Optic nerve
- Phosphodiesterase
ASJC Scopus subject areas
- Ophthalmology