Neuro-Behçet disease presenting with acute psychosis in an adolescent

Puja Patel, Mitchell Steinschneider, Alexis Boneparth, George Lantos

Research output: Contribution to journalArticlepeer-review

11 Scopus citations


Behçet disease is a systemic vasculitis of unknown etiology that can affect the neurologic system. Neuro-Behçet disease is not well defined in children and adolescents, and the diagnosis is difficult to make in this population as they often present with insufficient symptoms to meet diagnostic criteria. Psychiatric symptoms as the initial manifestation of neuro-Behçet disease has rarely been reported. We describe a 17-year-old boy who presented with acute psychosis and was subsequently diagnosed with neuro-Behçet disease. A rare combination of both cerebral venous thrombosis and parenchymal central nervous system involvement was identified by neuroimaging. Although treatment guidelines for neuro-Behçet disease are limited, the patient made demonstrative clinical and radiographic improvement with a combination of corticosteroids, anticoagulation, and immunosuppressants, including a tumor necrosis factor-α (TNFα) blocking agent.

Original languageEnglish (US)
Pages (from-to)NP86-NP91
JournalJournal of child neurology
Issue number9
StatePublished - Sep 2014


  • Acute psychosis
  • Anti-tumor necrosis factor-α
  • Cerebral venous thrombosis
  • Childhood
  • Neuro-Behçet disease

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Clinical Neurology


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