TY - JOUR
T1 - Multipurpose prevention technologies
T2 - The future of HIV and STI protection
AU - Fernández-Romero, José A.
AU - Deal, Carolyn
AU - Herold, Betsy C.
AU - Schiller, John
AU - Patton, Dorothy
AU - Zydowsky, Thomas
AU - Romano, Joe
AU - Petro, Christopher D.
AU - Narasimhan, Manjulaa
N1 - Funding Information:
We would like to thank Jennifer Brunet and Susanna Grecky at Population Council for their valuable input. This work was made possible by the generous support of the American people through the US Agency for International Development (USAID; grant AID-OAA-A-14-00009. This work was also supported by the National Institutes of Health (NIH; grant U19-AI103461). The contents of this paper are the sole responsibility of the authors and do not necessarily reflect the views of the funding agencies.
Publisher Copyright:
© 2015 Elsevier Ltd.
PY - 2015/7/1
Y1 - 2015/7/1
N2 - Every day, more than 1 million people are newly infected with sexually transmitted infections (STIs) that can lead to morbidity, mortality, and an increased risk of human immunodeficiency virus (HIV) acquisition. Existing prevention and management strategies, including behavior change, condom promotion, and therapy have not reduced the global incidence and prevalence, pointing to the need for novel innovative strategies. This review summarizes important issues raised during a satellite session at the first HIV Research for Prevention (R4P) conference, held in Cape Town, on October 31, 2014. We explore key STIs that are challenging public health today, new biomedical prevention approaches including multipurpose prevention technologies (MPTs), and the scientific and regulatory hurdles that must be overcome to make combination prevention tools a reality.
AB - Every day, more than 1 million people are newly infected with sexually transmitted infections (STIs) that can lead to morbidity, mortality, and an increased risk of human immunodeficiency virus (HIV) acquisition. Existing prevention and management strategies, including behavior change, condom promotion, and therapy have not reduced the global incidence and prevalence, pointing to the need for novel innovative strategies. This review summarizes important issues raised during a satellite session at the first HIV Research for Prevention (R4P) conference, held in Cape Town, on October 31, 2014. We explore key STIs that are challenging public health today, new biomedical prevention approaches including multipurpose prevention technologies (MPTs), and the scientific and regulatory hurdles that must be overcome to make combination prevention tools a reality.
KW - HIV
KW - HPV
KW - HSV-2
KW - Multipurpose prevention technologies
KW - STI
KW - Trichomonas vaginalis
UR - http://www.scopus.com/inward/record.url?scp=84937633540&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84937633540&partnerID=8YFLogxK
U2 - 10.1016/j.tim.2015.02.006
DO - 10.1016/j.tim.2015.02.006
M3 - Review article
C2 - 25759332
AN - SCOPUS:84937633540
SN - 0966-842X
VL - 23
SP - 429
EP - 436
JO - Trends in Microbiology
JF - Trends in Microbiology
IS - 7
ER -
