Multipurpose prevention technologies: The future of HIV and STI protection

José A. Fernández-Romero, Carolyn Deal, Betsy C. Herold, John Schiller, Dorothy Patton, Thomas Zydowsky, Joe Romano, Christopher D. Petro, Manjulaa Narasimhan

Research output: Contribution to journalReview articlepeer-review

61 Scopus citations


Every day, more than 1 million people are newly infected with sexually transmitted infections (STIs) that can lead to morbidity, mortality, and an increased risk of human immunodeficiency virus (HIV) acquisition. Existing prevention and management strategies, including behavior change, condom promotion, and therapy have not reduced the global incidence and prevalence, pointing to the need for novel innovative strategies. This review summarizes important issues raised during a satellite session at the first HIV Research for Prevention (R4P) conference, held in Cape Town, on October 31, 2014. We explore key STIs that are challenging public health today, new biomedical prevention approaches including multipurpose prevention technologies (MPTs), and the scientific and regulatory hurdles that must be overcome to make combination prevention tools a reality.

Original languageEnglish (US)
Pages (from-to)429-436
Number of pages8
JournalTrends in Microbiology
Issue number7
StatePublished - Jul 1 2015


  • HIV
  • HPV
  • HSV-2
  • Multipurpose prevention technologies
  • STI
  • Trichomonas vaginalis

ASJC Scopus subject areas

  • Microbiology
  • Microbiology (medical)
  • Virology
  • Infectious Diseases


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