Multicopper oxidases in saccharomyces cerevisiae and human pathogenic fungi

Tanmoy Chakraborty; Renáta Tóth; Joshua D. Nosanchuk; Attila Gácser

doi:10.3390/jof6020056

Multicopper oxidases in saccharomyces cerevisiae and human pathogenic fungi

Tanmoy Chakraborty, Renáta Tóth, Joshua D. Nosanchuk, Attila Gácser

Medicine

Research output: Contribution to journal › Review article › peer-review

3 Scopus citations

Abstract

Multicopper oxidases (MCOs) are produced by microscopic and macroscopic fungal species and are involved in various physiological processes such as morphogenesis, lignin degradation, and defense mechanisms to stress inducing environmental conditions as well as fungal virulence. This review will summarize our current understanding regarding the functions of MCOs present in Saccharomyces cerevisiae and in different human fungal pathogens. Of the two main MCO groups, the first group of MCOs is involved in iron homoeostasis and the second includes laccases. This review will also discuss their role in the pathogenesis of human fungal pathogens.

Original language	English (US)
Article number	56
Journal	Journal of Fungi
Volume	6
Issue number	2
DOIs	https://doi.org/10.3390/jof6020056
State	Published - Jun 2020

Keywords

Iron uptake
Laccase
Multicopper oxidases
Pathogenic fungi
Virulence

ASJC Scopus subject areas

Ecology, Evolution, Behavior and Systematics
Plant Science
Microbiology (medical)

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title = "Multicopper oxidases in saccharomyces cerevisiae and human pathogenic fungi",

abstract = "Multicopper oxidases (MCOs) are produced by microscopic and macroscopic fungal species and are involved in various physiological processes such as morphogenesis, lignin degradation, and defense mechanisms to stress inducing environmental conditions as well as fungal virulence. This review will summarize our current understanding regarding the functions of MCOs present in Saccharomyces cerevisiae and in different human fungal pathogens. Of the two main MCO groups, the first group of MCOs is involved in iron homoeostasis and the second includes laccases. This review will also discuss their role in the pathogenesis of human fungal pathogens.",

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AU - Chakraborty, Tanmoy

AU - Tóth, Renáta

AU - Nosanchuk, Joshua D.

AU - Gácser, Attila

PY - 2020/6

Y1 - 2020/6

N2 - Multicopper oxidases (MCOs) are produced by microscopic and macroscopic fungal species and are involved in various physiological processes such as morphogenesis, lignin degradation, and defense mechanisms to stress inducing environmental conditions as well as fungal virulence. This review will summarize our current understanding regarding the functions of MCOs present in Saccharomyces cerevisiae and in different human fungal pathogens. Of the two main MCO groups, the first group of MCOs is involved in iron homoeostasis and the second includes laccases. This review will also discuss their role in the pathogenesis of human fungal pathogens.

AB - Multicopper oxidases (MCOs) are produced by microscopic and macroscopic fungal species and are involved in various physiological processes such as morphogenesis, lignin degradation, and defense mechanisms to stress inducing environmental conditions as well as fungal virulence. This review will summarize our current understanding regarding the functions of MCOs present in Saccharomyces cerevisiae and in different human fungal pathogens. Of the two main MCO groups, the first group of MCOs is involved in iron homoeostasis and the second includes laccases. This review will also discuss their role in the pathogenesis of human fungal pathogens.

KW - Iron uptake

KW - Laccase

KW - Multicopper oxidases

KW - Pathogenic fungi

KW - Virulence

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JO - Journal of Fungi

JF - Journal of Fungi

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ER -

Multicopper oxidases in saccharomyces cerevisiae and human pathogenic fungi

Abstract

Keywords

ASJC Scopus subject areas

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