More on Neuropathy from Pyridoxine Abuse

Alan Berger, Herbert H. Schaumburg

Research output: Contribution to journalLetterpeer-review

26 Scopus citations


To the Editor: Pyridoxine (vitamin B6) megavitaminosis (over 2 g daily) has been reported to produce progressive sensory ataxia, which improves after discontinuation of the drug.* We describe patient who had the typical picture of pyridoxine-induced sensory ataxia while taking one 500-mg capsule daily. A 34-year-old woman sought medical attention because of progressive difficulty in walking. Three years previously, she had begun daily ingestion of a multivitamin containing 200 mg of vitamin B6. Two years later, she increased her daily intake to 500 mg, which was supplemented by an additional 300 mg no more than once.

Original languageEnglish (US)
Pages (from-to)986-987
Number of pages2
JournalNew England Journal of Medicine
Issue number15
StatePublished - Oct 11 1984

ASJC Scopus subject areas

  • Medicine(all)


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