Monoclonal gammopathies in the West of Ireland: A preliminary study

John M. Greally; Gerard O'Toole; Hugh McCann; Helen Grimes; Brian O'Connor; Gerard Solan; Niall Walsh; Ernest Egan

doi:10.1007/BF02937224

Monoclonal gammopathies in the West of Ireland: A preliminary study

John M. Greally, Gerard O'Toole, Hugh McCann, Helen Grimes, Brian O'Connor, Gerard Solan, Niall Walsh, Ernest Egan

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Abstract

A STUDY was carried out, based on laboratory test records of patients attending hospital, into the incidence of monoclonal gammopathy in the West of Ireland. Two hundred and ninety-six fully verified cases occurred in a seven and a half year period, giving an incidence for the study of 9.2 cases per population per annum. A diagnosis of malignancy was confirmed on 126 cases from the Western Health Board part of Connacht, either multiple myeloma (117 cases, or 47.4% of W.H.B. monoclonal gammo-pathies) or Waldenström's Macroglo-bulinaemia (9, 3.6%). The incidence of multiple myeloma was found to be 4.5 cases per 100,000 cases per annum. No diagnosis was obtained on many of the remaining 170 cases. A notable feature was the concentration of monoclonal gammopathy and multiple myeloma in certain areas. The basis for this variation is discussed.

Original language	English (US)
Pages (from-to)	94-101
Number of pages	8
Journal	Irish Journal of Medical Science
Volume	154
Issue number	3
DOIs	https://doi.org/10.1007/BF02937224
State	Published - Mar 1985
Externally published	Yes

ASJC Scopus subject areas

General Medicine

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title = "Monoclonal gammopathies in the West of Ireland: A preliminary study",

abstract = "A STUDY was carried out, based on laboratory test records of patients attending hospital, into the incidence of monoclonal gammopathy in the West of Ireland. Two hundred and ninety-six fully verified cases occurred in a seven and a half year period, giving an incidence for the study of 9.2 cases per population per annum. A diagnosis of malignancy was confirmed on 126 cases from the Western Health Board part of Connacht, either multiple myeloma (117 cases, or 47.4% of W.H.B. monoclonal gammo-pathies) or Waldenstr{\"o}m's Macroglo-bulinaemia (9, 3.6%). The incidence of multiple myeloma was found to be 4.5 cases per 100,000 cases per annum. No diagnosis was obtained on many of the remaining 170 cases. A notable feature was the concentration of monoclonal gammopathy and multiple myeloma in certain areas. The basis for this variation is discussed.",

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AU - Greally, John M.

AU - O'Toole, Gerard

AU - McCann, Hugh

AU - Grimes, Helen

AU - O'Connor, Brian

AU - Solan, Gerard

AU - Walsh, Niall

AU - Egan, Ernest

PY - 1985/3

Y1 - 1985/3

N2 - A STUDY was carried out, based on laboratory test records of patients attending hospital, into the incidence of monoclonal gammopathy in the West of Ireland. Two hundred and ninety-six fully verified cases occurred in a seven and a half year period, giving an incidence for the study of 9.2 cases per population per annum. A diagnosis of malignancy was confirmed on 126 cases from the Western Health Board part of Connacht, either multiple myeloma (117 cases, or 47.4% of W.H.B. monoclonal gammo-pathies) or Waldenström's Macroglo-bulinaemia (9, 3.6%). The incidence of multiple myeloma was found to be 4.5 cases per 100,000 cases per annum. No diagnosis was obtained on many of the remaining 170 cases. A notable feature was the concentration of monoclonal gammopathy and multiple myeloma in certain areas. The basis for this variation is discussed.

AB - A STUDY was carried out, based on laboratory test records of patients attending hospital, into the incidence of monoclonal gammopathy in the West of Ireland. Two hundred and ninety-six fully verified cases occurred in a seven and a half year period, giving an incidence for the study of 9.2 cases per population per annum. A diagnosis of malignancy was confirmed on 126 cases from the Western Health Board part of Connacht, either multiple myeloma (117 cases, or 47.4% of W.H.B. monoclonal gammo-pathies) or Waldenström's Macroglo-bulinaemia (9, 3.6%). The incidence of multiple myeloma was found to be 4.5 cases per 100,000 cases per annum. No diagnosis was obtained on many of the remaining 170 cases. A notable feature was the concentration of monoclonal gammopathy and multiple myeloma in certain areas. The basis for this variation is discussed.

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Monoclonal gammopathies in the West of Ireland: A preliminary study

Abstract

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