Modulation of host cell metabolism by Trypanosoma cruzi

S. A. Morris, H. B. Tanowitz, J. P. Bilezikian, M. Wittner

Research output: Contribution to journalArticlepeer-review

9 Scopus citations


Chagos disease, caused by the hemoflagellate Trypanosoma cruzi, is a complicated and devastating disease. It is hypothesized that an important target of infection may be the endothelial cell and that both the acute and chronic forms of the disease involve abnormalities in the microcirculotion. Stephen Morris and colleagues suggest that endothelial cell dysfunction occurs as a consequence of amastigote-associated interference in host cell metabolism.

Original languageEnglish (US)
Pages (from-to)82-87
Number of pages6
JournalParasitology Today
Issue number4
StatePublished - 1991

ASJC Scopus subject areas

  • Parasitology


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