Megacystis-microcolon-intestinal hypoperistalsis syndrome

Juan C. Kupferman, Charles L. Stewart, Dieter M. Schapfel, Frederick J. Kaskel, Richard N. Fine

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


The megacystis-microcolon-intestinal hypoperistalsis syndrome is a congenital disorder characterized by urinary bladder distension and hypoperistalsis throughout the entire gastrointestinal tract. We present a new case with the typical clinical, radiological, and pathological findings of the syndrome. The diagnosis should be suspected in a patient who presents clinically with intestinal obstruction and urinary retention, and confirmed with imaging studies, including abdominal plain films, urinary tract ultrasonography, and contrast studies of the colon and the bladder. The prognosis is generally very poor. Our patient died secondary to sepsis on day 5 of life.

Original languageEnglish (US)
Pages (from-to)626-627
Number of pages2
JournalPediatric Nephrology
Issue number5
StatePublished - Oct 1 1995
Externally publishedYes


  • Bladder
  • Hydronephrosis
  • Hypoperistalsis
  • Megacystis
  • Microcolon

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Nephrology


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