Megacystis-microcolon-intestinal hypoperistalsis and prune belly: Overlapping syndromes

Terry L. Levin, Lamia Soghier, Netta M. Blitman, Carlos Vega-Rich, Suhas Nafday

Research output: Contribution to journalArticlepeer-review

25 Scopus citations


Megacystis-microcolon-intestinal hypoperistalsis syndrome (MMIHS) is a rare, often fatal condition. Infants present with a functional obstruction of the gastrointestinal tract (GI), malrotation, microcolon, and a large nonobstructed bladder. Several features common to both MMIHS and Eagle-Barrett or prune belly syndrome (PBS) include hydronephrosis, bladder distension and laxity of the abdominal wall musculature. Additionally, MMIHS and PBS have been reported in the same family, suggesting the possibility of a common pathogenesis. MMIHS usually presents in female infants. We present a male infant diagnosed with both MMIHS and PBS. This is a unique case in which both MMIHS and true PBS are present in the same infant.

Original languageEnglish (US)
Pages (from-to)995-998
Number of pages4
JournalPediatric radiology
Issue number12
StatePublished - Dec 2004


  • Eagle-Barrett syndrome
  • Malrotation
  • Megacystis-microcolon-intestinal hypoperistalsis syndrome
  • Microcolon
  • Prunebelly syndrome

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Radiology Nuclear Medicine and imaging


Dive into the research topics of 'Megacystis-microcolon-intestinal hypoperistalsis and prune belly: Overlapping syndromes'. Together they form a unique fingerprint.

Cite this