Mechanism of 3 mercaptopicolinic acid inhibition of hepatic phosphoenolpyruvate carboxykinase (GTP)

Keyphrases

• Acid Inhibition 100%
• Phosphoenolpyruvate Carboxylase 100%
• Glucose Synthesis 100%
• Pig Liver 66%
• Mn2+ 66%
• Gluconeogenesis 66%
• Isolated Perfused Liver 33%
• Purified Enzymes 33%
• Hypoglycemic Activity 33%
• α-ketoglutarate (α-KG) 33%
• Dissociation Constant 33%
• Product Formation 33%
• Michaelis Constant 33%
• Inhibition Type 33%
• Minor Effect 33%
• Site of Action 33%
• Manganese(III) 33%
• Non-competitive Inhibitor 33%
• Liver Cytosol 33%
• Liver Mitochondria 33%
• Metal Ions 33%

Agricultural and Biological Sciences

• Phosphoenolpyruvate Carboxykinase (GTP) 100%
• Gluconeogenesis 100%
• Guinea Pig 60%
• Normal Value 20%
• Cytosol 20%
• Mitochondrion 20%

Immunology and Microbiology

• Gluconeogenesis 100%
• Liver Perfusion 40%
• Normal Value 20%
• Michaelis Constant 20%
• Dissociation Constant 20%
• Liver Cytosol 20%
• Liver Mitochondrion 20%