@article{93fa5523e2b346ab80be28838a7b70f9,
title = "Loss-of-function lesions impact B-cell development and fitness but are insufficient to drive CLL in mouse models",
author = "\{ten Hacken\}, Elisa and Shanye Yin and Robert Redd and S{\'a}nchez, \{Mar{\'i}a Hern{\'a}ndez\} and Kendell Clement and Hoffmann, \{Gabriela Brunsting\} and Regis, \{Fara F.\} and Elizabeth Witten and Shuqiang Li and Donna Neuberg and Luca Pinello and Livak, \{Kenneth J.\} and Wu, \{Catherine J.\}",
note = "Funding Information: Conflict-of-interest disclosure: C.J.W. is an equity holder of BioNTech Inc. and receives research funding from Pharmacyclics. L.P. has financial interests in Edilytics Inc. K.C. is an employee, shareholder, and officer of Edilytics Inc. The interests of L.P. and K.C. were reviewed and are managed by Massachusetts General Hospital and Partners HealthCare in accordance with their conflict-of-interest policies. The remaining authors declare no competing financial interests. Funding Information: Acknowledgments: The authors thank members of the Wu lab for the valuable discussions. The authors are also grateful for excellent technical assistance from the Dana-Farber Cancer Institute Animal Research Facility and the Dana-Faber Cancer Institute Flow Cytometry Core. This study was supported by grants from the National Institutes of Health/National Cancer Institute (P01 CA206978 and R01CA216273). E.t.H. is a scholar of the American Society of Hematology. S.Y. is supported by a research fellowship from the Lauri Strauss Leukemia Foundation and National Cancer Institute (R21 CA267527-01). M.H.S. has been supported by a Sara Borrell postdoctoral contract (CD19/00222) from the Instituto de Salud Carlos III (ISCIII), cofounded by Fondo Social Europeo “El Fondo Social Europeo invierte en tu futuro.” K.C. is supported by National Human Genome Research Institute Career Development Award K99HG011658. S.L. is supported by the National Cancer Institute Research Specialist Award (R50CA251956). L.P. is partially supported by National Human Genome Research Institute Genomic Innovator Award R35HG010717.",
year = "2023",
month = aug,
day = "16",
doi = "10.1182/bloodadvances.2022009135",
language = "English (US)",
volume = "7",
pages = "4514--4517",
journal = "Blood Advances",
issn = "2473-9529",
publisher = "American Society of Hematology",
number = "16",
}